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Displaying results 8291 - 8300 of 10000 in total
  1. Drug

    Phosphoaminophosphonic Acid-Adenylate Ester

    go.drugbank.com/drugs/DB04395
    Experimental

    An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. … It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. [PubChem]

  2. Drug

    VTX-801

    go.drugbank.com/drugs/DB17646
    Investigational

    It is being investigated in Wilson Disease.[L45924] … VTX-801 is a replication-deficient recombinant adeno-associated viral vector (rAAV) consisting of an AAV liver tropic capsid containing a single-stranded DNA genome carrying a shortened version of the

  3. Drug

    Sulopenem

    go.drugbank.com/drugs/DB15284
    Investigational

    Sulopenem is a penem antibacterial. It is marketed as the prodrug [sulopenem etzadroxil] in combination with [probenecid].[L51768]

  4. Drug

    Zinpentraxin alfa

    go.drugbank.com/drugs/DB14852
    Investigational

    It is under investigation in clinical trial NCT01981850 (A Phase 2 Study Of PRM-151 In Subjects With Myelofibrosis). … Zinpentraxin alfa is a recombinant form of PTX-2, a naturally circulating human protein.

  5. Drug

    Ligufalimab

    go.drugbank.com/drugs/DB17542
    Investigational

    It is under investigation in clinical trial NCT04900350 (A Trial of AK117 (Anti-cd47) in Patients With Myelodysplastic Syndrome). … Ligufalimab is a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting leukocyte surface antigen CD47.

  6. Drug

    Adermastat

    go.drugbank.com/drugs/DB28906
    Investigational

    Adermastat is a small molecule drug. … Adermastat is under investigation in clinical trial NCT03858686 (The Effect of FP-025, on Allergen-induced Airway Responses in Mild Eosinophilic House Dust Mite (HDM)-Allergic Asthma.).

  7. Drug

    Dimetotiazine

    go.drugbank.com/drugs/DB08967
    Approved

    Dimetotiazine has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions.

  8. Drug

    Fosigotifator

    go.drugbank.com/drugs/DB19409
    Investigational

    Fosigotifator is under investigation in clinical trial NCT05757141 (An Open-label Exploratory Study of ABBV-CLS-7262 Subjects With Vanishing White Matter Disease).

  9. Drug

    Imidocarb

    go.drugbank.com/drugs/DB11521
    ExperimentalVet approved

    Imidocarb is a urea derivative used in veterinary medicine as an antiprotozoal agent for the treatment of infection with Babesia and other parasites.

    Synonyms: N,N'-bis(3-(4,5-dihydro-1H-imidazol-2-yl)phenyl)urea
  10. Drug

    Aviscumine

    go.drugbank.com/drugs/DB12684
    Investigational

    Cy 503 is under investigation in clinical trial NCT00658437 (Aviscumine for the Treatment of Malignant Melanoma Stage IV After Failure of Prior Therapy).

    Categories: N-Glycosyl Hydrolases