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Ceftibuten
go.drugbank.com/drugs/DB01415ApprovedInvestigationalCeftibuten is a third-generation cephalosporin antibiotic that is orally-administered. … It is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
SAR445136
go.drugbank.com/drugs/DB17708InvestigationalHbF production in erythrocytes (RBC). … SAR445136 is an investigational zinc finger nuclease gene-edited cell therapy.
Volinanserin
go.drugbank.com/drugs/DB16351InvestigationalVolinanserin is under investigation in clinical trial NCT00464243 (Efficacy and Safety of Volinanserin on Sleep Maintenance Insomnia - Polysomnographic Study).
Dasiprotimut-T
go.drugbank.com/drugs/DB17287ExperimentalDasiprotimut-T is a personalized therapeutic vaccine against B-cell lymphomas.[A254701] It has been investigated in clinical trials.
Meglutol
go.drugbank.com/drugs/DB04377ExperimentalIt acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which … is the rate limiting enzyme in the biosynthesis of cholesterol.
Romifidine
go.drugbank.com/drugs/DB11543ExperimentalVet approvedRomifidine is a veterinary drug utilized as a sedative primarily in large animals, most frequently horses. It is also used less commonly in a wide variety of other animal species. … This drug's chemical structure closely resembles that of clonidine, however, romifidine is not approved for use in humans.
Nalorphine
go.drugbank.com/drugs/DB11490ExperimentalVet approvedIt is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence. … Nalorphine is a mixed opioid agonist–antagonist.
Arsthinol
go.drugbank.com/drugs/DB08928ExperimentalArsthinol (INN) is an antiprotozoal agent that was first synthesized by Ernst A.H. Friedheim in 1949 via the complexing of acetarsol with 2,3-dimercaptopropanol. … Considered well tolerated when compared to other related trivalent organoarsenicals, arsthinol has even undergone recent studies as a potential anticancer agent.
Amperozide
go.drugbank.com/drugs/DB08927ExperimentalAmperozide is a diphenylbutylpiperazine atypical antipsychotic which antagonizes 5-HT2A receptors. It inhibits dopamine release and alters the firing of dopaminergic neurons. … Alternatively, amperozide's main use lies in veterinary medicine, where it is typically employed to minimize aggression and stress in intensively farmed pigs.
Telisotuzumab adizutecan
go.drugbank.com/drugs/DB21832InvestigationalTelisotuzumab Adizutecan is a biologic drug. … Telisotuzumab Adizutecan is under investigation in clinical trial NCT06614192 (A Study Assessing Adverse Events and Disease Activity When Comparing Intravenously (IV) Infused ABBV-400 to Trifluridine and
Synonyms: Temab-A