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Rademikibart
go.drugbank.com/drugs/DB18995InvestigationalRademikibart is under investigation in clinical trial NCT04773678 (Efficacy and Safety of CBP-201 in Patients With Moderate to Severe Persistent Asthma With Type 2 Inflammation).
Plumbagin
go.drugbank.com/drugs/DB17048InvestigationalIt has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]
MB-102 CD123 CAR
go.drugbank.com/drugs/DB17366InvestigationalMB-102 are autologous T cells genetically modified to express CD123-specific, hinge-optimized CD28-costimulatory chimeric receptor and a truncated human epidermal growth factor receptor.
TAK-611
go.drugbank.com/drugs/DB17644InvestigationalFirst developed by Takeda, it is being investigated for the treatment of metachromatic leukodystrophy.
CD68-ET3-LV
go.drugbank.com/drugs/DB32864InvestigationalCD68-ET3-LV is an autologous gene therapy consisting of CD34+ hematopoietic stem and progenitor cells transduced ex-vivo with the CD68-ET3-LV lentiviral vector.
Reltecimod
go.drugbank.com/drugs/DB16687InvestigationalReltecimod is under investigation in clinical trial NCT02469857 (Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections).
Categories: Antigens, Differentiation, T-Lymphocyte, Costimulatory and Inhibitory T-Cell ReceptorsChlorhexadol
go.drugbank.com/drugs/DB01534IllicitInvestigationalChlorhexadol is a sedative and hypnotic which is regulated in the United States as a Schedule III controlled substance. It is a derivative of chloral hydrate.
Tosylchloramide
go.drugbank.com/drugs/DB14708InvestigationalTosylchloramide, also known as chloramine-T, is a chlorinated and deprotonated sulfonamide used as a mild disinfectant. It is not stable in the water dissolved form.
Salts: Chloramine-T, Chloramine-T trihydrateInternational brands: Chloramin TTebapivat
go.drugbank.com/drugs/DB19338InvestigationalTebapivat is under investigation in clinical trial NCT05490446 (A Study of Tebapivat (AG-946) in Participants With Anemia Due to Lower-risk Myelodysplastic Syndromes (LR-MDS)).
Amodiaquine
go.drugbank.com/drugs/DB00613ApprovedInvestigationalA 4-aminoquinoquinoline compound with anti-inflammatory properties.