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Displaying results 8321 - 8330 of 10000 in total
  1. Drug

    TO-901317

    go.drugbank.com/drugs/DB07080
    Experimental

    TO-901317 is an LXRalpha and LXRbeta agonist.

  2. Drug

    PHA-767491

    go.drugbank.com/drugs/DB17043
    Investigational

    PHA-767491 is a Cdc7/CDK9 inhibitor.[A253077]

  3. Drug

    Ilomastat

    go.drugbank.com/drugs/DB02255
    Experimental

    Ilomastat is a broad-spectrum matrix metalloproteinase inhibitor.

    Synonyms: (S-(R*,S*))-N(SUP 4)-HYDROXY-N(SUP 1)-(1H-INDOL-3-YLMETHYL)-2-(METHYLAMINO)-2-OXOETHYL)-2-(2-METHYLOPROPYL)BUTANEDIAMIDE, (R)-N(SUP 1)-HYDROXY-N-((S)-2-INDOL-3-YL-1-(METHYLCARBAMOYL)ETHYL)-2-ISOBUTYLSUCCINAMIDE
  4. Drug

    GW-3965

    go.drugbank.com/drugs/DB03791
    Experimental

    GW-3965 is a liver X receptor ligand.

  5. Drug

    Mericitabine

    go.drugbank.com/drugs/DB12045
    Investigational

    PSI-6130 is a pyrimidine nucleoside analog inhibitor of HCV RNA polymerase, an enzyme that is necessary for hepatitis C viral replication. … Mericitabine is a polymerase inhibitor being developed for the treatment of chronic hepatitis C. Mericitabine is a prodrug of PSI-6130, which demonstrated excellent potency in preclinical studies.

  6. Drug

    Bufotenine

    go.drugbank.com/drugs/DB01445
    ExperimentalIllicit

    Bufotenin has been used as a tool in CNS studies and misused as a psychedelic.

    Categories: Complex Mixtures
  7. Drug

    SOBI-003

    go.drugbank.com/drugs/DB15451
    Investigational

    SOBI-003 is a chemically modified variant of a recombinant human sulfamidase. … It is under investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA Patients).

  8. Drug

    Timdarpacept

    go.drugbank.com/drugs/DB17544
    Investigational

    IMM01 is a recombinant human signal regulatory protein α (SIRPα) IgG 1 fusion protein. … [A257261] IMM01 is under investigation in clinical trial NCT05140811 (A Study of IMM01 Combined With Azacitidine in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome).

  9. Drug

    AAV1-FS344

    go.drugbank.com/drugs/DB17855
    Investigational

    AAV1-FS344 is an investigational gene therapy developed by Milo Biotechnology to deliver follistatin, a potent myostatin inhibitor. … It is being investigated for the treatment of Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, and inclusion body myositis.[L46742, L46747, L46752]

  10. Drug

    SRP-9005

    go.drugbank.com/drugs/DB17958
    Investigational

    SRP-9005 is a rAAVrh74 vector containing a codon-optimized human SGCG transgene. … Developed by the Kurt+Peter Foundation and Sarepta Therapeutics, it is being investigated for the treatment of Limb-girdle muscular dystrophy (LGMD) type 2C/R5.[A260142]