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Ocedurenone
go.drugbank.com/drugs/DB21519InvestigationalOcedurenone is under investigation in clinical trial NCT04968184 (Efficacy and Safety of KBP-5074 in Uncontrolled Hypertension and Moderate or Severe Chronic Kidney Disease (CKD)). … The usage of the INN stem '-renone' in the name indicates that Ocedurenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist.
Selnoflast
go.drugbank.com/drugs/DB21522InvestigationalSelnoflast is under investigation in clinical trial NCT05924243 (A Study to Investigate The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7486967 in Participants With Early Idiopathic … The usage of the INN stem '-noflast' in the name indicates that Selnoflast is a inflammasome protein NLRP3 inhibitor.
Brimarafenib
go.drugbank.com/drugs/DB21706InvestigationalBrimarafenib is under investigation in clinical trial NCT04249843 (Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants with Advanced or Refractory Tumors). … The usage of the INN stem '-rafenib' in the name indicates that Brimarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor.
Efimosfermin alfa
go.drugbank.com/drugs/DB28564InvestigationalEfimosfermin Alfa is under investigation in clinical trial NCT07221188 (A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected
Crobenetine
go.drugbank.com/drugs/DB21095InvestigationalCrobenetine is under investigation in clinical trial NCT02273466 (Pharmacokinetics of Oral Desipramine With and Without Concomitant Administration of Crobenetine Infusion in Healthy Male Subjects).
Dalzanemdor
go.drugbank.com/drugs/DB21549InvestigationalDalzanemdor is under investigation in clinical trial NCT05655520 (A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease).
Fedovapagon
go.drugbank.com/drugs/DB11734InvestigationalFedovapagon has been used in trials studying the treatment of Nocturia.
Cirtuvivint
go.drugbank.com/drugs/DB17269InvestigationalCirtuvivint is a first-in-class CDC-like kinase (CLK) inhibitor.
Synonyms: 4-pyridinecarboxamide, 2-(4-methyl-1-piperazinyl)-n-(6-(1-methyl-1h-pyrazol-4-yl)-3-isoquinolinyl)-Apc001
go.drugbank.com/drugs/DB17819ExperimentalApc001 is an aptamer developed for the treatment of osteogenesis imperfecta.
Daniquidone
go.drugbank.com/drugs/DB12804InvestigationalDaniquidone has been used in trials studying the treatment of Neoplasms.