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Guretolimod
go.drugbank.com/drugs/DB21487InvestigationalGuretolimod is under investigation in clinical trial NCT03416335 (A Study of DSP-0509 in Patients With Advanced Solid Tumors to Determine the Safety and the Pharmacokinetic Profile). … The usage of the INN stem '-tolimod' in the name indicates that Guretolimod is a toll-like receptor (TLR) agonist.
Ocedurenone
go.drugbank.com/drugs/DB21519InvestigationalOcedurenone is under investigation in clinical trial NCT04968184 (Efficacy and Safety of KBP-5074 in Uncontrolled Hypertension and Moderate or Severe Chronic Kidney Disease (CKD)). … The usage of the INN stem '-renone' in the name indicates that Ocedurenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist.
Selnoflast
go.drugbank.com/drugs/DB21522InvestigationalSelnoflast is under investigation in clinical trial NCT05924243 (A Study to Investigate The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7486967 in Participants With Early Idiopathic … The usage of the INN stem '-noflast' in the name indicates that Selnoflast is a inflammasome protein NLRP3 inhibitor.
Brimarafenib
go.drugbank.com/drugs/DB21706InvestigationalBrimarafenib is under investigation in clinical trial NCT04249843 (Study of Safety, Pharmacokinetics, and Antitumor Activity of BGB-3245 in Participants with Advanced or Refractory Tumors). … The usage of the INN stem '-rafenib' in the name indicates that Brimarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor.
Abivertinib
go.drugbank.com/drugs/DB15327InvestigationalThe study is expected to be completed in March 2021.[L17398] … [L17383] It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies.
Zoalene
go.drugbank.com/drugs/DB11480ExperimentalVet approvedDinitolmide is a fodder additive for prophylaxis against coccidiosis infections in poultry.
Lunasine
go.drugbank.com/drugs/DB16223InvestigationalLunasine is under investigation in clinical trial NCT02709330 (ALS Reversals - Lunasin Regimen).
CT103A
go.drugbank.com/drugs/DB18180InvestigationalCT103A is an investigational BCMA-targeted genetically modified autologous T-cell immunotherapy.
CT120
go.drugbank.com/drugs/DB18181InvestigationalCT120 is an investigational autologous CD19/22 targeted CAR-T cell immunotherapy.
CAM-101
go.drugbank.com/drugs/DB18414InvestigationalCAM-101 is an allogeneic human platelet lysate product depleted of fibrinogen.