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Displaying results 8351 - 8360 of 10000 in total
  1. Drug

    Ergocalciferol

    go.drugbank.com/drugs/DB00153
    ApprovedInvestigationalNutraceutical

    Ergocalciferol is an inactivated vitamin D analog.[A177526] It is synthesized by some plants in the presence of UVB light. … [T580] Ergocalciferol is considered the first vitamin D analog and is differentiated from [cholecalciferol] by the presence of a double bond between C22 and C23 and the presence of a methyl group at

    Mixtures: Se-Natal, Cal/mag 2:1 With DCategories: Vitamin D and Analogues
  2. Drug

    Icosapent

    go.drugbank.com/drugs/DB00159
    ApprovedInvestigationalNutraceutical

    -2 and prostaglandin-2 families. … It serves as the precursor for the prostaglandin-3 and thromboxane-3 families.

    Mixtures: Se-Plete DHA, Se-Tan DHACategories: Fatty Acids, Omega-3, Non COX-2 selective NSAIDS
  3. Drug

    Ramipril

    go.drugbank.com/drugs/DB00178
    ApprovedInvestigational

    Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).

    Mixtures: DELMUNO 5/5 MG, RAMI/AMLODIPIN RATIO 5/5Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Pentagastrin

    go.drugbank.com/drugs/DB00183
    Approved

    It has also been used as a diagnostic aid. … A synthetic pentapeptide that mimics the actions of endogenous gastrin when given parenterally. It works by stimulating the secretion of gastric acid, pepsin, and intrinsic factor.

  5. Drug

    Phentermine

    go.drugbank.com/drugs/DB00191
    ApprovedIllicitInvestigational

    Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug. … [A174361, A174364] It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine.

    Categories: Cytochrome P-450 Substrates, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: Adipex-P, TERFAMEX T
  6. Drug

    Indecainide

    go.drugbank.com/drugs/DB00192
    Approved

    Indecainide is a rarely used antidysrhythmic. … Indecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics

  7. Drug

    Vidarabine

    go.drugbank.com/drugs/DB00194
    ApprovedWithdrawn

    A nucleoside antibiotic isolated from Streptomyces antibioticus. … It has some antineoplastic properties and has broad spectrum activity against DNA viruses in cell cultures and significant antiviral activity against infections caused by a variety of viruses such as the

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 9-β-D-arabinofuranosyl-9H-purin-6-amine, 9-β-D-arabinofuranosyladenine
  8. Drug

    Oseltamivir

    go.drugbank.com/drugs/DB00198
    ApprovedInvestigational

    [A179086] Yearly vaccination with the influenza vaccine is still considered the best preventative measure. … Oseltamivir (marketed as the product TamifluⓇ), is an antiviral neuraminidase inhibitor used for the treatment and prophylaxis of infection with influenza viruses A (including pandemic H1N1) and B.

    Synonyms: Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate, 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha,4beta,5alpha))-Products: TAMIFLU® CAPSULAS 75 MG, TAZAMIR(R) CAPSULA 75 MG
  9. Drug

    Hydroxocobalamin

    go.drugbank.com/drugs/DB00200
    ApprovedInvestigational

    Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. … It is also used in cyanide poisoning, Leber's optic atrophy, and toxic amblyopia.

    Mixtures: TRIBEDOCE C/L, ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL (5+5)Categories: Vitamin B Complex, Heterocyclic Compounds, 1-Ring
  10. Drug

    Ticlopidine

    go.drugbank.com/drugs/DB00208
    Approved

    The FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients' WBC and platelets when they … It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Inhibitors