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ABBV-514
go.drugbank.com/drugs/DB17586InvestigationalABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.[L45464]
Plozalizumab
go.drugbank.com/drugs/DB12520InvestigationalPlozalizumab has been investigated for the treatment of Atherosclerosis.
Linaprazan glurate
go.drugbank.com/drugs/DB21534InvestigationalLinaprazan glurate has a monoisotopic molecular weight of 480.24 Da.
Chlorophyll B
go.drugbank.com/drugs/DB04506ExperimentalIt has the atomic symbol Mg, atomic number 12, and atomic weight 24.31.
Mirfentanil
go.drugbank.com/drugs/DB09175ExperimentalAt high doses, it exhibits analgesic activity which is not fully reversed by opioid antagonists, suggesting that the drug has both opioid and non-opioid mechanisms of action.
Lunsotogene parvec
go.drugbank.com/drugs/DB18278ApprovedInvestigational[L56135,L56136] This landmark decision followed designations as a Regenerative Medicine Advanced Therapy (RMAT) and Fast Track, marking the first-ever gene therapy approved to restore a neurosensory function
GX-19 Vaccine
go.drugbank.com/drugs/DB15891InvestigationalAs of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].
5'-Guanosine-Diphosphate-Monothiophosphate
go.drugbank.com/drugs/DB01864ExperimentalA stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific
Nelistotug
go.drugbank.com/drugs/DB19334InvestigationalNelistotug is under investigation in clinical trial NCT06062420 (A Platform Study of Novel Immunotherapy Combinations as First-line Treatment in Participants With PD-L1 Positive Recurrent/metastatic Squamous
Epratuzumab
go.drugbank.com/drugs/DB04958InvestigationalThis agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus.