5'-Guanosine-Diphosphate-Monothiophosphate

DB01864ExperimentalSmall molecule

Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation,...

Formula / weight: C₁₀H₁₆N₅O₁₃P₃S · 539.246 g/mol (avg)
Also known as: gamma-Thio-GTP · GTP gamma S · Guanosine 5'-(gamma-S)triphosphate · guanosine 5'-[gamma-thio]triphosphate · Guanosine 5'-O-(3-thiotriphosphate)

Resolves to

Compound

UNIIEJ7Q9D2M9DCAS37589-80-3ChEMBLCHEMBL1204628ChEBI43000PubChem37792KEGGC01806

Structure

InChIKeyXOFLBQFBSOEHOG-UUOKFMHZSA-NSMILESNC1=NC2=C(N=CN2[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=S)[C@@H](O)[C@H]2O)C(=O)N1

Targets

P62330ARF6Q08188TGM3P9WN95ftsZP62491RAB11A

What you can answer from here — as of September 13, 2026

4Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with 5'-Guanosine-Diphosphate-Monothiophosphate, and which of those have an active Phase 3 trial?

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