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Dolcanatide
go.drugbank.com/drugs/DB13112InvestigationalDolcanatide has been investigated in Exposure.
N,N-dimethylarginine
go.drugbank.com/drugs/DB01686ExperimentalAsymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. … ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health.
Synonyms: guanidino-N,N-dimethylarginine, N(G),N(G)-DimethylarginineRuserontinib
go.drugbank.com/drugs/DB21555InvestigationalRuserontinib is under investigation in clinical trial NCT04716114 (A Study of SKLB1028 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory (R/R) AML With FLT3-Mutated). … The usage of the INN stem '-tinib' in the name indicates that Ruserontinib is a tyrosine kinase inhibitor.
Enbezotinib
go.drugbank.com/drugs/DB21565InvestigationalEnbezotinib is under investigation in clinical trial NCT04161391 (Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations). … The usage of the INN stem '-tinib' in the name indicates that Enbezotinib is a tyrosine kinase inhibitor.
QRX-411
go.drugbank.com/drugs/DB17868ExperimentalIt addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777] … QRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein.
Spermidine
go.drugbank.com/drugs/DB03566InvestigationalIt is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures.
Synonyms: N-(3-Aminopropyl)-1,4-butane-diamine, N-(3-aminopropyl)butane-1,4-diamineSRD-001
go.drugbank.com/drugs/DB25902InvestigationalSRD-001 is under investigation in clinical trial NCT06224660 (Modulation of SERCA2a of Intra-Myocytic Calcium Trafficking in Cardiomyopathy Secondary to Duchenne Muscular Dystrophy).
Drostanolone
go.drugbank.com/drugs/DB00858ExperimentalIllicitDrostanolone is indicated in postmenopausal women with recurrent breast cancer, in a combined hormone therapy.
LGD-6972
go.drugbank.com/drugs/DB14779InvestigationalLGD-6972 is under investigation in clinical trial NCT01919684 (Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LGD-6972 in Healthy Subjects and Subjects With Type 2 Diabetes
BN‐Brachyury vaccine
go.drugbank.com/drugs/DB17425ExperimentalBN‐Brachyury vaccine is a novel prime‐boost therapeutic cancer immunotherapy. It is composed of the [MVA-BN-brachyury-TRICOM vaccine] and the fowlpox virus(FPV)‐Brachyury booster vaccine.[A255173]
Synonyms: BN‐Brachyury vaccine