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Lutetium Lu 177-DTPA-omburtamab
go.drugbank.com/drugs/DB31015InvestigationalLutetium Lu 177-DTPA-omburtamab is a radioimmunoconjugate made up of [omburtamab] conjugated with lutetium Lu 177 via the chelating agent of diethylenetriaminepentaacetic acid (DTPA).[L54566]
CX-052075
go.drugbank.com/drugs/DB31655ApprovedCX-052075 is a nucleoside-modified messenger RNA (mRNA) encoding the N-terminal domain (NTD) and receptor-binding domain (RBD) of the spike glycoprotein of the SARS-CoV-2 Omicron variant sublineage LP.8.1 … spike protein, allowing for a more targeted immune response and the use of a significantly smaller amount of mRNA per dose.
FRAX597
go.drugbank.com/drugs/DB31734ExperimentalFRAX597 is a small molecule drug that inhibits the p21-activated kinases (PAKs).[A274673, A274678]
Categories: Heterocyclic Compounds, 1-RingCopper histidinate
go.drugbank.com/drugs/DB32041ApprovedMenkes disease is a rare, X-linked recessive disorder caused by pathogenic variants in the ATP7A gene, which encodes a copper transport protein essential for absorbing dietary copper and transporting it … [A275383] Copper histidinate is a subcutaneously-administered copper-histidine complex that allows for copper supplementation in patients with defective ATP7A transporters.
IL21120033
go.drugbank.com/drugs/DB32508ExperimentalIL21120033 is a first-in-class, small-molecule selective CXCR7 agonist.
ZKN-013
go.drugbank.com/drugs/DB32582ExperimentalZKN-013 is a readthrough inducer under investigation for rare dermatological diseases.[L56075]
SW033291
go.drugbank.com/drugs/DB32765ExperimentalSW033291 is a small molecule 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor. … [A275473, A275474] It has been found to increase prostaglandin E2 (PGE2) and is being investigated in accelerating of hematopoietic recovery and treating type 2 diabetes mellitus.[A275473, A275474]
Synonyms: 2-(Butane-1-sulfinyl)-4-phenyl-6-thiophen-2-yl-thieno[2,3-b]pyridin-3-ylamineCategories: Heterocyclic Compounds, 1-RingGLB-008
go.drugbank.com/drugs/DB32800ExperimentalGLB-008 is a molecular glue degrader targeting VAV1.[L56125, L56126]
XM146-MPA-SN38
go.drugbank.com/drugs/DB32865ExperimentalXM146-MPA-SN38 is a PDL1-targeting polypeptide-MPA-SN38 conjugate.
TN-301
go.drugbank.com/drugs/DB32867ExperimentalTN-301 is a small-molecule histone deacetylase 6 inhibitor.