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Displaying results 8371 - 8380 of 10000 in total
  1. Drug

    SI-109

    go.drugbank.com/drugs/DB32603
    Experimental

    SI-109 is a potent, small-molecule inhibitor of the STAT3 SH2 domain.[A275443]

  2. Drug

    Batefenterol

    go.drugbank.com/drugs/DB12526
    Investigational

    Batefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.

    Categories: Adrenergic beta-2 Receptor Agonists
  3. Drug

    MLN8054

    go.drugbank.com/drugs/DB13061
    Investigational

    MLN8054 has been used in trials studying the treatment of Colon Neoplasm, Breast Neoplasm, Bladder Neoplasm, Pancreatic Neoplasm, and Advanced Malignancies.

  4. Drug

    MVA-BN-brachyury-TRICOM vaccine

    go.drugbank.com/drugs/DB17424
    Investigational

    of T-cell co-stimulatory molecules (TRICOM), which is comprised of the three human immune-enhancing co-stimulatory molecules B7-1, ICAM-1 and LFA-3. … [L44513] MVA-BN-brachyury-TRICOM vaccine is administered as a priming vaccine, followed by the administration of the fowlpox virus(FPV)‐Brachyury booster vaccine.

  5. Drug

    Vevorisertib

    go.drugbank.com/drugs/DB21481
    Investigational

    The usage of the INN stem '-sertib' in the name indicates that Vevorisertib is a serine/threonine kinase inhibitor.

  6. Drug

    GTB-3550

    go.drugbank.com/drugs/DB18494
    Investigational

    GTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form

    Synonyms: single chain recombinant trispecific killer engager consistent of anti-CD16 scFV spliced to anti-CD33 scFV with a modified IL-15 linker
  7. Drug

    Cagrilintide

    go.drugbank.com/drugs/DB18887
    Investigational

    Cagrilintide is under investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated

  8. Drug

    Nicotinamide Mononucleotide

    go.drugbank.com/drugs/DB03227
    Investigational

    A nucleotide in which the nitrogenous base, nicotinamide, is in beta-N-glycosidic linkage with the C-1 position of D-ribose. Synonyms: Nicotinamide Ribonucleotide; NMN. [PubChem]

  9. Drug

    Prostaglandin D2

    go.drugbank.com/drugs/DB02056
    Experimental

    Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects. … The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages.

  10. Drug

    SB-269970

    go.drugbank.com/drugs/DB13988
    Experimental

    In the studies performed with this agent, it has been suggested that SB-269970 acts either as a selective antagonist or inverse agonist of the serotonin receptor 7 (5-HT7).[A31816,A31817]