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AVI-4020
go.drugbank.com/drugs/DB05873InvestigationalAVI-4020 is a neugene antisense drug candidate for the treatment of patients with acute West Nile virus disease who have serious neurological impairment (WNV neuroinvasive disease).
JQ1
go.drugbank.com/drugs/DB17021ExperimentalFirst-in-class potent and selective inhibitor of the BRD4 signaling pathway.[A252967]
Suratadenoturev
go.drugbank.com/drugs/DB18672InvestigationalSuratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.
Synonyms: A replication-competent adenovirus type 5 in which the E1A and E1B genes are under the control of a human telomerase reverse transcriptase (hTERT) and IRES, respectively., A recombinant replication-competent adenovirus type 5 (Ad-5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and replaced by an expression cassette containingMSX-122
go.drugbank.com/drugs/DB12715InvestigationalMSX-122 has been used in trials studying the treatment of Solid Tumors.
Alvircept sudotox
go.drugbank.com/drugs/DB12786InvestigationalAlvircept Sudotox has been used in trials studying the treatment of HIV Infections.
MK-7622
go.drugbank.com/drugs/DB12897InvestigationalMK-7622 has been used in trials studying the treatment of Alzheimer's Disease.
TT-301
go.drugbank.com/drugs/DB12899InvestigationalTT301 has been used in trials studying the treatment of Traumatic Brain Injury.
XL-888
go.drugbank.com/drugs/DB12981InvestigationalXL888 has been used in trials studying the treatment of Cancer and Melanoma.
LY-518674
go.drugbank.com/drugs/DB12988InvestigationalLY518674 has been used in trials studying the treatment of Metabolic Syndrome X.
Henatinib
go.drugbank.com/drugs/DB13019InvestigationalHenatinib has been used in trials studying the treatment of Advanced Solid Cancer.