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Choline
go.drugbank.com/drugs/DB00122ApprovedInvestigationalNutraceuticalA basic constituent of lecithin that is found in many plants and animal organs. … It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Synonyms: N,N,N-trimethylethanol-ammonium, Vitamin JMixtures: Pour Ma Santé, C. Vit-min FormulaAnakinra
go.drugbank.com/drugs/DB00026ApprovedInvestigationalUnlike native human IL-1Ra, anakinra has an additional methionine residue at the amino terminus. … [L35415] Since IL-1 has an important role in inflammation and immunological responses, anakinra is also used for the off-label treatment of inflammatory diseases.
Synonyms: Interleukin-1 receptor antagonist anakinraCategories: Interleukin-1 Receptor AntagonistBrompheniramine
go.drugbank.com/drugs/DB00835ApprovedHistamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Synonyms: 3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine, 3-(p-bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamineMixtures: Brom Mal Phenyl HCl Dex HBr, J-tan D PdRO-6870810
go.drugbank.com/drugs/DB15151InvestigationalRO-6870810 is under investigation in clinical trial NCT02308761 (A Study of RO6870810/TEN-010 in Participants With Acute Myeloid Leukemia and Myelodysplastic Syndrome).
Categories: Heterocyclic Compounds, 1-RingSynonyms: BET INHIBITOR TEN-010, 2-[(4S)-6-(4-chlorophenyl)-1,7,8-trimethylthiophenol[3,2-f]1,2,4-triazolo[4,3-a]1,4-diazepin-4-yl]-N-[3-(4-methylpiperazinyl)propyl]acetamideUrea C-13
go.drugbank.com/drugs/DB09510ApprovedInvestigationalBoth forms can be used within the Urea Breath Test, however some may prefer 13C as it is non-radioactive compared to 14C, which may be preferable in pregnant women and children. … Exhaled breath samples can then be collected and measured for the presence of radioactivity.
Synonyms: Urea 13 C, Urea C 13Products: HELICOBACTER TEST INFAI (C-URE) 75 MG 1 SISE, TAU-KIT® 100 MGBarzolvolimab
go.drugbank.com/drugs/DB18934InvestigationalBarzolvolimab is under investigation in clinical trial NCT06455202 (A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria (CSU)).
Synonyms: Immunoglobulin G1 [233-alanine,234-glutamine,251-tyrosine,253-threonine,255-glutamic acid,321-glutamine,de-C-terminal-lysine], anti-(human receptor tyrosine kinase KIT extracellular domain) (human-MusDabrafenib
go.drugbank.com/drugs/DB08912ApprovedInvestigational[L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene.[L41955] … Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexProducts: TAFINLAR®75 MG CÁPSULAS DURAS, TAFINLAR® 50 MG CÁPSULAS DURASD-alpha-Tocopherol acetate
go.drugbank.com/drugs/DB14002ApprovedNutraceuticalVet approvedAlpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E. … This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number
Synonyms: Vitamin E acetate, D-, D-alpha tocoferil acetateMixtures: Vitamin A C E W.niacinam.beta Car.and Min., Coen.q10w.vit.c and E Beta-car.se Cu Zn MnValganciclovir
go.drugbank.com/drugs/DB01610ApprovedInvestigationalValganciclovir hydrochloride (Valcyte, manufactured by Roche) is an antiviral medication used to treat cytomegalovirus infections. … As the L-valyl ester of ganciclovir, it is actually a prodrug for ganciclovir. After oral administration, it is rapidly converted to ganciclovir by intestinal and hepatic esterases.
Categories: Heterocyclic Compounds, 2-RingProducts: GANOCIP®, TRASGARIV®