Brompheniramine is a histamine H1 antagonist used to treat coughs, upper respiratory symptoms, and nasal congestion associated with allergies and the common cold.
- Mechanism
- Curator reviewed
Brompheniramine is an antagonist of the H1 histamine receptors with moderate antimuscarinic actions, as with other common antihistamines such as diphenhydramine. Due to its anticholindergic effects, brompheniramine may cause drowsiness, sedation, dry mouth, dry throat, blurred vision, and increased heart rate.
- Primary indication
- For the treatment of the symptoms of the common cold and allergic rhinitis, such as runny nose, itchy eyes, watery eyes, and sneezing.Curator reviewed · 24 structured indications
- Formula / weight
- C16H19BrN2 · 319.239 g/mol (avg)
- First approval
- Canada, 2000 · United States, 1985
- Code names
- AHR 1843 · D 721
- Brand names
Resolves to
Clinical / RWD
Structure
InChIKey
ZDIGNSYAACHWNL-UHFFFAOYSA-NSMILESCN(C)CCC(C1=CC=C(Br)C=C1)C1=CC=CC=N1What you can answer from here — as of September 23, 2026
6Protein targetsEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Brompheniramine, and which of those have an active Phase 3 trial?
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