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Displaying results 8411 - 8420 of 10000 in total
  1. Drug

    Pabinafusp alfa

    go.drugbank.com/drugs/DB15633
    Investigational

    Pabinafusp alfa is under investigation in clinical trial NCT03568175 (A Study of JR-141 in Patients With Mucopolysaccharidosis II).

    Synonyms: -2-SULFATASE, DISULFIDE WITH HUMAN-MUS MUSCULUS MONO, Immunoglobulin G1-kappa, anti-(human transferrin receptor 1, tfr1) humanized monoclonal antibody, fused with human iduronate-2-sulfatase, glycoform alfa:
  2. Drug

    CDC-801

    go.drugbank.com/drugs/DB15640
    Investigational

    CDC-801 is under investigation in clinical trial NCT00006097 (Chemotherapy in Treating Patients With Chronic Lymphocytic Leukemia).

  3. Drug

    Fasitibant

    go.drugbank.com/drugs/DB15646
    Investigational

    Fasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee).

    Synonyms: 1-piperazinepentanaminium, .delta.-amino-4-((4-(((2,4-dichloro-3-(((2,4-dimethyl-8-quinolinyl)oxy)methyl)phenyl)sulfonyl)amino)tetrahydro-2h-pyran-4-yl)carbonyl)-n,n,n-trimethyl-.epsilon.
  4. Drug

    Ad5-nCoV

    go.drugbank.com/drugs/DB15655
    Investigational

    Ad5-nCoV is a recombinant adenovirus type-5 vector (Ad5) vaccine currently being investigated for prophylaxis against SARS-CoV-2. … The study will evaluate antibody response in healthy patients between the ages of 18 and 60 who will receive one of three study doses, with follow-up taking place at weeks 2 and 4 and months 3 and 6 post-vaccination

    Synonyms: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)
  5. Drug

    Ala-geninthiocin

    go.drugbank.com/drugs/DB15657
    Experimental

    Ala-geninthiocin is a novel thiopeptide antibacterial compound derived from marine _Streptomyces_ species.

  6. Drug

    N4-Hydroxycytidine

    go.drugbank.com/drugs/DB15660
    Experimental

    N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions. … [A193017] N4-hydroxycytodine has been shown to inhibit SARS-CoV-2 as well as other human and bat coronaviruses in mice and human airway epithelial cells.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: beta-D-N-4-Hydroxycytidine, 4-N-Hydroxycytidine
  7. Drug

    Molnupiravir

    go.drugbank.com/drugs/DB15661
    Investigational

    [A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed _in vivo_, and distributes into tissues where it becomes the active 5’-triphosphate form. … Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of [N4-hydroxycytidine].

    Categories: Heterocyclic Compounds, 1-RingProducts: LAGEVRIO® 200MG CAPSULAS
  8. Drug

    Besifovir

    go.drugbank.com/drugs/DB15671
    Investigational

    Categories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Sisunatovir

    go.drugbank.com/drugs/DB15674
    Investigational

    Sisunatovir is under investigation in clinical trial NCT04267822 (Study of RV521 in the Treatment of Adult Subjects Who Have Undergone HCT With an URTI With RSV).

    Categories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Baloxavir

    go.drugbank.com/drugs/DB15675
    Investigational

    Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-Ring