Baloxavir

DB15675InvestigationalSmall moleculePolymerase Acidic Endonuclease Inhibitors

Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).

Chemical structure of Baloxavir
Mechanism
Curator reviewed
Formula / weight
C24H19F2N3O4S · 483.49 g/mol (avg)
Code names
S-033447

Resolves to

Clinical / RWD
Structure
InChIKeyFIDLLEYNNRGVFR-CTNGQTDRSA-NSMILES[H][C@@]12COCCN1C(=O)C1=C(O)C(=O)C=CN1N2[C@@H]1C2=C(SCC3=C1C=CC(F)=C3F)C=CC=C2
Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
14Drug interactionsStructured to mechanism, not free text
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4Clinical trialsPhase, status and sponsor resolved per trial
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4+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Baloxavir, and which of those have an active Phase 3 trial?

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