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CA-074 methyl ester
go.drugbank.com/drugs/DB07223ExperimentalCA-074 methyl ester (CA-074Me) is a cell-permeable cathepsin B inhibitor. It is converted by cellular esterases to CA-074.[A258234,A258239]
Synonyms: (S)-methyl 1-((2S,3S)-3-methyl-2-((2S,3S)-3-(propylcarbamoyl)oxirane-2-carboxamido)pentanoyl)pyrrolidine-2-carboxylate, Methyl (2S)-1-[(2S,3S)-3-methyl-2-[[(2S,3S)-3-(propylcarbamoyl)oxirane-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carboxylateDisitamab vedotin
go.drugbank.com/drugs/DB17208InvestigationalDisitamab vedotin is an antibody-drug conjugate drug targeting human epidermal growth factor receptor 2 (HER2). It is currently being investigated for cancers.[A254721]
Ixmyelocel-T
go.drugbank.com/drugs/DB17601InvestigationalIxmyelocel-T is an expanded, autologous multicellular therapy cultured from bone-marrow mononuclear cells. Developed by Vericel Corporation, it is being investigated for cardiomyopathy.
Epitizide
go.drugbank.com/drugs/DB13989ExperimentalEpitizide is an agent, commonly found in combination [triamterene], used to produce diuresis.
AZD-7325
go.drugbank.com/drugs/DB13994InvestigationalAZD7325 is a high affinity, selective modulator of the GABAA receptor system. [L2936]
Formononetin
go.drugbank.com/drugs/DB15335ExperimentalFormononetin is under investigation in clinical trial NCT02174666 (Isoflavone Treatment for Postmenopausal Osteopenia.).
Preimplantation factor
go.drugbank.com/drugs/DB16301InvestigationalPreimplantation factor is under investigation in clinical trial NCT03593460 (Phase II Autoimmune Hepatitis).
KDT-3594
go.drugbank.com/drugs/DB17085InvestigationalKDT-3594 is a non-ergot dopamine receptor agonist developed by Kissei Pharmaceutical.
BI-1206
go.drugbank.com/drugs/DB17429InvestigationalBI-1206 is a fully human immunoglobulin G1 monoclonal antibody that targets CD32b.
APR-548
go.drugbank.com/drugs/DB17546InvestigationalAPR-548 is an analog of [eprenetapopt] and a reactivator of mutant p53.