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Displaying results 8421 - 8430 of 10000 in total
  1. Drug

    Ad5-nCoV

    go.drugbank.com/drugs/DB15655
    Investigational

    Ad5-nCoV is a recombinant adenovirus type-5 vector (Ad5) vaccine currently being investigated for prophylaxis against SARS-CoV-2. … The study will evaluate antibody response in healthy patients between the ages of 18 and 60 who will receive one of three study doses, with follow-up taking place at weeks 2 and 4 and months 3 and 6 post-vaccination

    Synonyms: Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)
  2. Drug

    Ala-geninthiocin

    go.drugbank.com/drugs/DB15657
    Experimental

    Ala-geninthiocin is a novel thiopeptide antibacterial compound derived from marine _Streptomyces_ species.

  3. Drug

    N4-Hydroxycytidine

    go.drugbank.com/drugs/DB15660
    Experimental

    N4-Hydroxyctidine, or EIDD-1931, is a ribonucleoside analog which induces mutations in RNA virions. … [A193017] N4-hydroxycytodine has been shown to inhibit SARS-CoV-2 as well as other human and bat coronaviruses in mice and human airway epithelial cells.

    Synonyms: beta-D-N-4-Hydroxycytidine, 4-N-HydroxycytidineCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Molnupiravir

    go.drugbank.com/drugs/DB15661
    Investigational

    [A193014,A193026] With improved oral bioavailability in non-human primates, it is hydrolyzed _in vivo_, and distributes into tissues where it becomes the active 5’-triphosphate form. … Molnupiravir (EIDD-2801, MK-4482) is the isopropylester prodrug of [N4-hydroxycytidine].

    Categories: Heterocyclic Compounds, 1-RingProducts: LAGEVRIO® 200MG CAPSULAS
  5. Drug

    Besifovir

    go.drugbank.com/drugs/DB15671
    Investigational

    Categories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Sisunatovir

    go.drugbank.com/drugs/DB15674
    Investigational

    Sisunatovir is under investigation in clinical trial NCT04267822 (Study of RV521 in the Treatment of Adult Subjects Who Have Undergone HCT With an URTI With RSV).

    Categories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Baloxavir

    go.drugbank.com/drugs/DB15675
    Investigational

    Baloxavir is under investigation in clinical trial NCT04327791 (Combination Therapy With Baloxavir and Oseltamavir 1 for Hospitalized Patients With Influenza (The COMBO Trial 1)).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 3-Ring
  8. Drug

    Neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen

    go.drugbank.com/drugs/DB15683
    ApprovedInvestigational

    Synonyms: Neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen, Nimenrix component neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen
  9. Drug

    Tridecactide

    go.drugbank.com/drugs/DB15687
    Investigational

    Tridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects. … [A203210] Tridecactide, along with [metenkefalin], are under investigation as an immunomodulatory therapy for moderate to severe COVID-19.[L13874,L13877]

    Synonyms: alpha-1-13-corticotropin, human
  10. Drug

    Azoximer bromide

    go.drugbank.com/drugs/DB15689
    Investigational

    Azoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19).

    Synonyms: Poly((1-(carboxymethyl)piperazin-1-ium-1,4-diyl bromide)ethylene-co-((piperazin-1,4-diyl 1-oxide)ethylene)Categories: Heterocyclic Compounds, 1-Ring