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Rocacetrapib
go.drugbank.com/drugs/DB15437InvestigationalRocacetrapib is under investigation in clinical trial NCT02156544 (Study to Investigate the Safety/Tolerability and Pharmacokinetics/Pharmacodynamics of CKD-519).
Sapanisertib
go.drugbank.com/drugs/DB11836InvestigationalSapanisertib has been used in trials studying the treatment of HCC, Solid Tumor, Gliosarcoma, Liver Cancer, and Glioblastoma, among others.
TAK-448
go.drugbank.com/drugs/DB11975InvestigationalTAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.
Exatecan
go.drugbank.com/drugs/DB12185InvestigationalExatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.
Renzapride
go.drugbank.com/drugs/DB04917InvestigationalRenzapride is currently in Phase III clinical development in the United States for the treatment of constipation-predominant irritable bowel syndrome (IBS-C). … It has been suggested that renzapride is effective in the treatment of irritable bowel syndrome with alternating stool pattern. It is being developed by Alizyme of the UK.
Cixutumumab
go.drugbank.com/drugs/DB12250InvestigationalIGF-IR is overexpressed in a variety of tumour types. … Cixutumumab has been used in trials studying the treatment of Lung Cancer, Malignant Neoplasm, Leukemia, Mast-Cell, Non-Small-Cell Lung Carcinoma, and Adenocarcinoma of the Prostate.
Halofuginone
go.drugbank.com/drugs/DB04866InvestigationalVet approvedFood and Drug Administration in March, 2000. … Halofuginone also effectively suppresses tumor progression and metastasis in mice.
(1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid
go.drugbank.com/drugs/DB03455ExperimentalThese are compounds containing an acetic acid (or a derivative) linked to the C3 carbon atom of an indole. (1H-indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid is known to target interleukin-2.
Decoquinate
go.drugbank.com/drugs/DB11394ExperimentalVet approvedDecoquinate is used in veterinary to delay the growth and reproduction of coccidian parasites.
Bersanlimab
go.drugbank.com/drugs/DB17377InvestigationalBersanlimab is an investigational monoclonal antibody directed against intercellular adhesion molecule 1 (ICAM-1).