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FF-10101-01
go.drugbank.com/drugs/DB16050InvestigationalFF-10101-01 is under investigation in clinical trial NCT03194685 (Study of FF-10101-01 in Patients With Relapsed or Refractory Acute Myeloid Leukemia).
Darovasertib
go.drugbank.com/drugs/DB16059InvestigationalIDE-196 is under investigation in clinical trial NCT03947385 (Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions).
Bemarituzumab
go.drugbank.com/drugs/DB16105InvestigationalBemarituzumab is under investigation in clinical trial NCT03694522 (A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (Mfolfox6) in Gastric/gastroesophageal Junction Cancer (FIGHT)).
GSK-945237
go.drugbank.com/drugs/DB15345InvestigationalGSK-945237 is under investigation in clinical trial NCT01039610 (A Single Center Four Part Study in Healthy Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose … and Repeat Escalating Oral Doses of GSK945237; the Effect of Linezolid on Hematology Safety Parameters; and the Effects of GSK945237 and Moxifloxacin on QTc.).
Gevokizumab
go.drugbank.com/drugs/DB12119InvestigationalGevokizumab acts as a modulator of cytokine imbalance in IL-1 mediated disease states. It has a very high binding affinity of 300fM and blocks the activation of IL-1 receptors. … Gevokizumab has been used in trials studying the treatment of Acne Vulgaris, Osteoarthritis, Behcet's Uveitis, Pyoderma Gangrenosum, and Behcet's Disease Uveitis, among others.
Fuzapladib
go.drugbank.com/drugs/DB19478ExperimentalFuzapladib is a small molecule drug. The usage of the INN stem '-pladib' in the name indicates that Fuzapladib is a phospholipase A2 inhibitor.
Ponalrestat
go.drugbank.com/drugs/DB19717ExperimentalPonalrestat is a small molecule drug. The usage of the INN stem '-restat' in the name indicates that Ponalrestat is a aldose reductase inhibitor.
Vatinoxan
go.drugbank.com/drugs/DB19781ExperimentalVatinoxan is a small molecule drug. The usage of the INN stem '-oxan(e)' in the name indicates that Vatinoxan is a benzodioxane derivative. Vatinoxan has a monoisotopic molecular weight of 418.17 Da.
Flesinoxan
go.drugbank.com/drugs/DB19853ExperimentalFlesinoxan is a small molecule drug. The usage of the INN stem '-oxan(e)' in the name indicates that Flesinoxan is a benzodioxane derivative.
Solimastat
go.drugbank.com/drugs/DB19872ExperimentalSolimastat is a small molecule drug. The usage of the INN stem '-mastat' in the name indicates that Solimastat is a matrix metalloproteinase inhibitor.