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Displaying results 8451 - 8460 of 10000 in total
  1. Drug

    Zavacorilant

    go.drugbank.com/drugs/DB21509
    Investigational

    Zavacorilant is under investigation in clinical trial NCT04672512 (Single and Multiple Ascending Dose Study of CORT125329 in Healthy Participants). … The usage of the INN stem '-corilant' in the name indicates that Zavacorilant is a glucocorticoid receptor antagonist (non-steroidal).

  2. Drug

    Leukotriene C4

    go.drugbank.com/drugs/DB08855
    Experimental

    It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. … It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and Related Compounds, 1990)

    Synonyms: (R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)glycine
  3. Drug

    Xiliertinib

    go.drugbank.com/drugs/DB21453
    Investigational

    Xiliertinib is under investigation in clinical trial NCT02601274 (Study of Theliatinib (HMPL-309) in Patients With Advanced Solid Tumor). Xiliertinib has a monoisotopic molecular weight of 442.21 Da. … The usage of the INN stem '-ertinib' in the name indicates that Xiliertinib is a epidermal growth factor receptor (EGFR) inhibitor.

  4. Drug

    Paltimatrectinib

    go.drugbank.com/drugs/DB21588
    Investigational

    Paltimatrectinib is under investigation in clinical trial NCT04901806 (Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors). … The usage of the INN stem '-trectinib' in the name indicates that Paltimatrectinib is a tropomyosin receptor kinase (TRK) inhibitor.

  5. Drug

    Cannabigerol

    go.drugbank.com/drugs/DB14734
    Investigational

    A natural product found in Cannabis sativa and Helichrysum species.

  6. Drug

    Cannabichromene

    go.drugbank.com/drugs/DB14735
    Investigational

    A natural product found in Cannabis sativa and Helichrysum species.

  7. Drug

    GB1211

    go.drugbank.com/drugs/DB17499
    Investigational

    GB1211 is an orally active galectin-3 (Gal-3) inhibitor.

  8. Drug

    RAPA-201

    go.drugbank.com/drugs/DB18446
    Investigational

    RAPA-201 is an autologous rapamycin-resistant T-cell therapy.

  9. Drug

    Givastomig

    go.drugbank.com/drugs/DB18618
    Investigational

    Givastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody.

    Synonyms: an anti-Claudin 18.2 and 4.1BB Bispecific Antibody
  10. Drug

    CN-201

    go.drugbank.com/drugs/DB18726
    Investigational

    CN-201 is a humanized anti-CD3/CD19 bispecific antibody.