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Etrolizumab
go.drugbank.com/drugs/DB12189Investigational[A244564, A244569, A244579, A244584] A recent class of drugs designed to impair lymphocyte homing, so-called "anti-trafficking agents" (ATAs), have shown some success and include approved drugs such as … [A244564, A244584] Etrolizumab is a humanized IgG1κ monoclonal antibody directed against the β7 subunit of gastrointestinal α4β7 and αEβ7 integrins that, due to its target specificity, appears as or more
Lenabasum
go.drugbank.com/drugs/DB12193InvestigationalAjulemic acid has been used in trials studying the treatment of Cystic Fibrosis, Dermatomyositis, and Diffuse Cutaneous Systemic Sclerosis.
Synonyms: (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene-9-carboxylic acidCategories: Interleukin-1, antagonists & inhibitorsVP-14637
go.drugbank.com/drugs/DB12195InvestigationalMDT-637 has been investigated for the treatment of Drug Safety.
Categories: Heterocyclic Compounds, 1-RingTivantinib
go.drugbank.com/drugs/DB12200InvestigationalTivantinib has been investigated in Solid Tumors.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingTozadenant
go.drugbank.com/drugs/DB12203InvestigationalTozadenant has been investigated for the basic science of Cocaine Dependence.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingN-6022
go.drugbank.com/drugs/DB12206InvestigationalN6022 has been used in trials studying the treatment of Asthma and Cystic Fibrosis.
Categories: Heterocyclic Compounds, 1-RingVerdinexor
go.drugbank.com/drugs/DB12207InvestigationalKpt 335 is under investigation in clinical trial NCT02431364 (Trial of Safety and Tolerability of Oral Verdinexor (Verdinexor) in Healthy Adults).
Categories: Heterocyclic Compounds, 1-RingPSI-697
go.drugbank.com/drugs/DB12211InvestigationalPSI-697 has been used in trials studying the treatment of Scleritis.
Categories: P-Selectin, Heterocyclic Compounds, 2-RingBergapten
go.drugbank.com/drugs/DB12216InvestigationalBergapten is under investigation in clinical trial NCT00533195 (Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis).
Synonyms: 5 methoxypsoralen, 5-methoxypsoralenCategories: Cytochrome P-450 CYP3A Inhibitors, Heterocyclic Compounds, 1-RingLurtotecan
go.drugbank.com/drugs/DB12222InvestigationalLurtotecan is under investigation in clinical trial NCT00022594 (Liposomal Lurtotecan in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer).