Etrolizumab

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Etrolizumab
Accession Number
DB12189
Description

Etrolizumab has been used in trials studying the treatment of Crohn Disease and Ulcerative Colitis.

Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
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Protein Chemical Formula
Not Available
Protein Average Weight
Not Available
Sequences
Not Available
Synonyms
Not Available

Pharmacology

Indication
Not Available
Contraindications & Blackbox Warnings
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbciximabThe risk or severity of adverse effects can be increased when Abciximab is combined with Etrolizumab.
AdalimumabThe risk or severity of adverse effects can be increased when Adalimumab is combined with Etrolizumab.
AlemtuzumabThe risk or severity of adverse effects can be increased when Alemtuzumab is combined with Etrolizumab.
AlirocumabThe risk or severity of adverse effects can be increased when Alirocumab is combined with Etrolizumab.
Anthrax immune globulin humanThe risk or severity of adverse effects can be increased when Anthrax immune globulin human is combined with Etrolizumab.
Antilymphocyte immunoglobulin (horse)The risk or severity of adverse effects can be increased when Antilymphocyte immunoglobulin (horse) is combined with Etrolizumab.
Antithymocyte immunoglobulin (rabbit)The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Etrolizumab.
Asfotase alfaThe risk or severity of adverse effects can be increased when Asfotase alfa is combined with Etrolizumab.
AtezolizumabThe risk or severity of adverse effects can be increased when Atezolizumab is combined with Etrolizumab.
AtoltivimabThe risk or severity of adverse effects can be increased when Etrolizumab is combined with Atoltivimab.
Additional Data Available
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    Extended Description
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  • Severity
    Severity
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  • Evidence Level
    Evidence Level
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  • Action
    Action
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Food Interactions
Not Available

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available

Chemical Identifiers

UNII
I2A72G2V3J
CAS number
1044758-60-2

References

General References
Not Available
PubChem Substance
347911296
Wikipedia
Etrolizumab

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Active Not RecruitingTreatmentUlcerative Colitis1
3CompletedTreatmentUlcerative Colitis4
3RecruitingTreatmentCrohn's Disease (CD)2
2CompletedTreatmentUlcerative Colitis1
1Active Not RecruitingTreatmentCrohn's Disease (CD) / Ulcerative Colitis1
1CompletedNot AvailableHealthy Volunteers1
1CompletedHealth Services ResearchHealthy Volunteers1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on October 20, 2016 15:34 / Updated on June 12, 2020 10:53

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