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Displaying results 841 - 850 of 10000 in total
  1. Drug

    Isopropyl myristate

    go.drugbank.com/drugs/DB13966
    Approved

    [A178078] At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse [A32333, L1964, L1966]. … Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.

    Synonyms: 1-Methylethyl tetradecanoate
  2. Target

    Pyroglutamyl-peptidase 1

    go.drugbank.com/bio_entities/BE0020171
    TargetHumans

    Removes 5-oxoproline from various penultimate amino acid residues except L-proline

    Synonyms: PAP-I, PGP-I
  3. Indication

    Myeloblastic Leukemia

    go.drugbank.com/conditions/DBCOND0042219
    Drugs: Daunorubicin
    Synonyms: Myeloid leukemia, no ICD-O subtype (morphologic abnormality), Myeloid leukemia, no International Classification of Diseases for Oncology subtype
  4. Drug

    Amiodarone

    go.drugbank.com/drugs/DB01118
    ApprovedInvestigational

    Because of its ability to cause serious toxicity and possibly death, amiodarone use should be reserved for its approved indications, according to prescribing information.[L3561,L11265,L11286] … Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.

    Synonyms: 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran, 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuranInternational brands: Amio-Aqueous IV
  5. Target

    Aminoglycoside 3'-phosphotransferase

    go.drugbank.com/bio_entities/BE0003548
    EnzymeEscherichia coli

    Resistance to kanamycin and structurally-related aminoglycosides, including amikacin.

    Synonyms: APH(3')I, APH(3')-I
  6. Drug

    5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine

    go.drugbank.com/drugs/DB07140
    Experimental

    Synonyms: 5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
  7. Drug

    Camphor

    go.drugbank.com/drugs/DB01744
    ApprovedInvestigationalWithdrawn

    The FDA ruled that camphorated oil could not be marketed in the United States and that no product could contain a concentration higher than 11%. … [A254252,L43942] However, camphor can be found in several nonprescription medications at lower concentrations.[A254252]

    Synonyms: D-Camphor, (R)-camphorMixtures: Zam-Buk Ointment, Pharmacys Prescription Vapor Rub
  8. Drug

    Benzydamine

    go.drugbank.com/drugs/DB09084
    ApprovedInvestigational

    aspirin-like NSAIDs but facilitate benzydamine's mechanism of action as an effective locally-acting NSAID with local anaesthetic and analgesic properties. … Moreover, unlike aspirin-like NSAIDs which are acids or metabolised to acids, benzydamine is in fact a weak base.

    Mixtures: KLOROBEN FORT 3 MG/ML+ 2 MG/ML GARGARA, 200 ML, KLOROBEN FORT 3 MG/ML+ 2 MG/ML ORAL SPREY, 40 MLCategories: Non COX-2 selective NSAIDS, Anti-Inflammatory Agents, Non-Steroidal
  9. Drug

    Filgrastim

    go.drugbank.com/drugs/DB00099
    ApprovedInvestigational

    It has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_. … [L40714] Filgrastim was approved in the US in 1991 and there are biosimilars available with similar therapeutic indications.[A245858] Tbo-filgrastim was approved by the FDA on August 29, 2012.

    Synonyms: r-metHuG-CSFInternational brands: White-C
  10. Indication

    Pseudohypoparathyroidism

    go.drugbank.com/conditions/DBCOND0008696
    Drugs: Dihydrotachysterol
    Synonyms: Pseudohypoparathyroidism type I A (disorder)