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Avanafil
go.drugbank.com/drugs/DB06237Approved[L32113] It first received FDA approval on April 27, 2012,[L32058] with subsequent EMA approval in June 2013.[L32113] … Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used in the treatment of erectile dysfunction.
Categories: Drugs Used in Erectile DysfunctionSynonyms: (S)-4-(3-Chloro-4-methoxybenzylamino)-2-(2-hydroxymethylpyrrolidin-1-yl)-N-pyrimidin-2-ylmethyl-5-pyrimidinecarboxamideAcemetacin
go.drugbank.com/drugs/DB13783ApprovedInvestigational[A31352] In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin.[T50] It was developed by E. … Merck and Company in Germany as an attempt to provide a safer drug but other than the amelioration on the gastrointestinal effects, the metabolism of acetamicin led to the formation of indomethacin and
Products: RANTUDIL ® LP 90 MG CAPSULAS DE LIBERACIÓN PROLONGADABinimetinib
go.drugbank.com/drugs/DB11967ApprovedInvestigational[A34275,L3335] On June 27, 2018, the Food and Drug Administration approved the combination of [Encorafenib] and binimetinib (BRAFTOVI and MEKTOVI, from Array BioPharma Inc.) in combination for patients … with unresectable or metastatic melanoma with the BRAF V600E or V600K mutations, as detected by an FDA-approved test.
Products: MEKTOVI® 15 MG TABLETAS RECUBIERTAS, Mektovı 15 mg Film Kaplı Tablet, 84 ADETBromocriptine
go.drugbank.com/drugs/DB01200ApprovedInvestigationalWithdrawnBromocriptine has been associated with pulmonary fibrosis, and can also cause sustained suppression of somatotropin (growth hormone) secretion in some patients with acromegaly. … In 1995, the FDA withdrew the approval of bromocriptine mesylate for the prevention of physiological lactation after finding that bromocriptine was not shown to be safe for use.
Products: Co Bromocriptine Tablets 2.5mg, BROMOCRIPTINE MESYLATE TABLETS USPGanirelix
go.drugbank.com/drugs/DB06785ApprovedInvestigational[L43045] The first case of pregnancy achieved after the use of ganirelix in an assisted reproduction program was reported in 1998.[A252195] Ganirelix was first approved by the FDA on July 29, 1999. … Ganirelix is indicated for controlled ovarian hyperstimulation in assisted reproduction techniques.
Products: NOVOLEX 0.25 MG/0.5 ML SOLUCIÓN INYECTABLE EN JERINGA PRECARGADA, Ganirelix Astro 0,25 mg/0,5 ml Injektionslösung in einer FertigspritzeRifapentine
go.drugbank.com/drugs/DB01201ApprovedInvestigationalRifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells.
Products: Rifapentine Tablets, PRIFTIN FILM COATED TABLETS 150MGNeratinib
go.drugbank.com/drugs/DB11828ApprovedInvestigationalNeratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. … Neratinib is currently under investigation for use in many other forms of cancer.
Products: NERLYNX FILM-COATED TABLETS 40 MG, NERLYNX (neratinib) Film-Coated Tablets 40 mgAtazanavir
go.drugbank.com/drugs/DB01072ApprovedInvestigationalAtazanavir is distinguished from other PIs in that it can be given once daily (rather than requiring multiple doses per day) and has lesser effects on the patient's lipid profile (the amounts of cholesterol … and other fatty substances in the blood).
Mixtures: VIRALNICH® TABLETAS RECUBIERTASCategories: Antivirals used in combination for the treatment of HIV infectionsAluminum sesquichlorohydrate
go.drugbank.com/drugs/DB11108ApprovedAluminum sesquichlorohydrate is an aluminum salt used as an antiperspirant agent, cosmetic astringent and deodorant agent. It works by physically blocking eccrine sweat gland ducts [A31171].
Mixtures: Lactovit DEO ROLL-ON LACTOUREA DEODORANT ANTIPERSPIRANT, Lactovit DEO ROLL ON LACTOUREA DEODORANT ANTIPERSPIRANTProducts: Pur Desir De Lys Creme Deodorante Antisudorifique, Pur Desir De Rose Creme Deodorante AntisudorifiquePioglitazone
go.drugbank.com/drugs/DB01132ApprovedInvestigational[A19759] Thiazolidinediones, including pioglitazone, have fallen out of favor in recent years due to the presence of multiple adverse effects and warnings regarding their use (e.g. congestive heart … Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.
Mixtures: PIOGLITAZONE E METFORMINA EG, PIOGLITAZONE E METFORMINA EGCategories: Drugs Used in Diabetes