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Piribedil
go.drugbank.com/drugs/DB12478InvestigationalPiribedil has been investigated in Parkinson's Disease.
Categories: Heterocyclic Compounds, 1-RingBetulinic Acid
go.drugbank.com/drugs/DB12480ApprovedWithdrawnBetulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
Categories: Non COX-2 selective NSAIDSSGI-1776
go.drugbank.com/drugs/DB12494InvestigationalSGI-1776 has been used in trials studying the treatment of Prostate Cancer, Non-Hodgkins Lymphoma, and Relapsed/Refractory Leukemias.
Categories: Heterocyclic Compounds, 1-RingCilansetron
go.drugbank.com/drugs/DB04885ExperimentalCilansetron is a 5HT-3 antagonist made by Solvay Pharmaceuticals that is currently under trial phase in the EU and US.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingBrecanavir
go.drugbank.com/drugs/DB04887InvestigationalIn December of 2006 GSK announced a decision to discontinue the development of brecanavir for the treatment of HIV. The decision was based on issues regarding the formulation of the drug.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingPhenserine
go.drugbank.com/drugs/DB04892InvestigationalPhenserine is a next generation acetylcholinesterase (AChE) inhibitor indicated for the treatment of AD. … Phenserine is under development by Axonyx, a US biopharmaceutical company that focuses on treatments for dementia.
Categories: Heterocyclic Compounds, 2-RingLucinactant
go.drugbank.com/drugs/DB04897ApprovedFDA approved on March 6, 2012. … It contains sinapultide, a novel, hydrophobic, 21-amino acid peptide (leucine and lysine repeating units, KL4 peptide) designed to mimic human surfactant protein-B (SB-P).
Nesiritide
go.drugbank.com/drugs/DB04899ApprovedInvestigationalWithdrawnNesiritide is a 32 amino acid recombinant human B-type natriuretic peptide. … Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing).
Renzapride
go.drugbank.com/drugs/DB04917InvestigationalRenzapride is currently in Phase III clinical development in the United States for the treatment of constipation-predominant irritable bowel syndrome (IBS-C).
Categories: Serotonin 5-HT4 Receptor AgonistsDesmoteplase
go.drugbank.com/drugs/DB04925InvestigationalDesmoteplase is a recombinant form of vampire bat DSPA (Salivary plasminogen activator alpha 1). … When a vampire bat bites its victim, it secretes an enzyme that prevents the blood from clotting.
Synonyms: rDSPA alpha 1, Salivary plasminogen activator alpha 1, Desmodus rotundus