Piribedil

DB12478InvestigationalSmall molecule

Piribedil is a dopamine agonist used with or without levodopa in the treatment of Parkinson's disease.

Chemical structure of Piribedil
Mechanism
Curator reviewed
Formula / weight
C16H18N4O2 · 298.346 g/mol (avg)
Code names
ET-495 · EU-4200

Resolves to

Compound
UNIIDO22K1PRDJCAS3605-01-4ChEMBLCHEMBL1371770ChEBI92833PubChem4850
Clinical / RWD
RxNorm8353ATCN04BC08
Structure
InChIKeyOQDPVLVUJFGPGQ-UHFFFAOYSA-NSMILESC(N1CCN(CC1)C1=NC=CC=N1)C1=CC2=C(OCO2)C=C1
Targets
P35462DRD3P14416DRD2P18825ADRA2CP21917DRD4P08908HTR1AP41595HTR2B

What you can answer from here — as of January 29, 2025

6Protein targetsEach mapped to UniProt, with action and pharmacological action
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103Drug interactionsStructured to mechanism, not free text
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3Clinical trialsPhase, status and sponsor resolved per trial
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2Structured indicationsCondition, population, route and combination as fields, not prose
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4ContraindicationsEach with its own population and attribute set
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6Marketed productsAcross 5 countries and 5 labellers
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1ATC codeIncluding every combination product, plus 10 drug categories
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22+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Piribedil, and which of those have an active Phase 3 trial?

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