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Displaying results 8511 - 8520 of 10000 in total
  1. Drug

    ABX-196

    go.drugbank.com/drugs/DB16339
    Investigational

    ABX-196 is under investigation in clinical trial NCT03897543 (ABX196 in Combination With Nivolumab in Patients With Hepatocellular Carcinoma).

  2. Drug

    Ulevostinag

    go.drugbank.com/drugs/DB14721
    Investigational

    Upon intratumoral (IT) administration, STING agonist MK-1454 binds to STING and activates the STING pathway, which promotes IKK-related kinase TANK-binding kinase 1 (TBK1) signaling and activates nuclear … factor-kappa B (NF-kB) and interferon regulatory factor 3 (IRF3) in immune cells in the tumor microenvironment; this leads to the production of pro-inflammatory cytokines, including interferons (IFNs)

  3. Drug

    Opnurasib

    go.drugbank.com/drugs/DB21583
    Investigational

    Opnurasib is a small molecule drug. The usage of the INN stem '-rasib' in the name indicates that Opnurasib is a Ras protein inhibitor. … Opnurasib is under investigation in clinical trial NCT05132075 (Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer

  4. Drug

    Furaprofen

    go.drugbank.com/drugs/DB06499
    Experimental

  5. Drug

    Cutamesine

    go.drugbank.com/drugs/DB06618
    Investigational

  6. Drug

    Praconase

    go.drugbank.com/drugs/DB05584
    Investigational

  7. Drug

    Reloxaliase

    go.drugbank.com/drugs/DB15560
    Investigational

    Reloxaliase is under investigation in clinical trial NCT03456830 (Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria). … Reloxaliase is a crystalline formulation of oxalate decarboxylase derived from _Bacillus Subtilis_.

  8. Drug

    AEF0117

    go.drugbank.com/drugs/DB27675
    Investigational

    AEF0117 is a small molecule drug. AEF0117 is under investigation in clinical trial NCT05554926 (Study of [4-14C] AEF0117 Following a Single Oral Dose in Healthy Male Subjects).

  9. Drug

    MWN117

    go.drugbank.com/drugs/DB33969
    Experimental

    MWN117 is a small molecule drug. MWN117 is under investigation in clinical trial NCT07824804 (Phase 1 Clinical Study of MWN117 Injection in Healthy Participants and Participants With Obesity).

  10. Drug

    Tifacogin

    go.drugbank.com/drugs/DB06437
    Investigational