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Displaying results 8511 - 8520 of 10000 in total
  1. Drug

    Tralesinidase alfa

    go.drugbank.com/drugs/DB17657
    Investigational

    Tralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. … It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known as Sanfilippo syndrome B.[A258828]

  2. Drug

    NSI-566

    go.drugbank.com/drugs/DB17954
    Investigational

    NSI-566 is a stem cell therapy consisting of human spinal cord-derived neural stem cells. … Developed by Seneca Biopharma, it is being investigated for the treatment of amyotrophic lateral sclerosis (ALS), stroke, and chronic spinal cord injury (cSCI).[L47097]

  3. Drug

    Drozitumab

    go.drugbank.com/drugs/DB19106
    Investigational

    It was developed by Genentech as a drug for the treatment of cancers … Drozitumab is a human monoclonal antibody directed against tumor necrosis factor receptor superfamily member 10B (TNFRSF10B), a member of tumor necrosis factor related apoptosis-inducing ligand (TRAIL)

  4. Drug

    Prostaglandin D2

    go.drugbank.com/drugs/DB02056
    Experimental

    The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages.

  5. Drug

    Irampanel

    go.drugbank.com/drugs/DB21123
    Investigational

    Irampanel has a monoisotopic molecular weight of 309.15 Da. … Irampanel is under investigation in clinical trial NCT02222961 (Single Increasing Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Male Volunteers).

  6. Drug

    Aftobetin

    go.drugbank.com/drugs/DB20425
    Investigational

    Aftobetin has a monoisotopic molecular weight of 452.23 Da. … Aftobetin is under investigation in clinical trial NCT02928211 (Aftobetin-HCl and Fluorescence Detection Measured by Sapphire II to Determine the Number and Timing of Administrations).

  7. Drug

    Azilsartan mopivabil

    go.drugbank.com/drugs/DB21569
    Experimental

    Azilsartan mopivabil has a monoisotopic molecular weight of 676.25 Da. … The usage of the INN stem '-sartan' in the name indicates that Azilsartan mopivabil is a angiotensin II receptor antagonist, antihypertensive (non-peptidic).

  8. Drug

    Riselcaftor

    go.drugbank.com/drugs/DB21685
    Experimental

    Riselcaftor has a monoisotopic molecular weight of 516.17 Da. … The usage of the INN stem '-caftor' in the name indicates that Riselcaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier.

  9. Drug

    Quinezamide

    go.drugbank.com/drugs/DB19459
    Experimental

    Quinezamide has a monoisotopic molecular weight of 240.1 Da.

  10. Drug

    Darsidomine

    go.drugbank.com/drugs/DB19460
    Experimental

    Darsidomine has a monoisotopic molecular weight of 196.13 Da.