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Displaying results 8511 - 8520 of 10000 in total
  1. Drug

    Vilzemetkib

    go.drugbank.com/drugs/DB21704
    Experimental

    Vilzemetkib is a small molecule drug. The usage of the INN stem '-metkib' in the name indicates that Vilzemetkib is a MET (mesenchymal epithelial transition factor) kinase inhibitor. … Vilzemetkib has a monoisotopic molecular weight of 642.27 Da.

  2. Drug

    Zandatrigine

    go.drugbank.com/drugs/DB19051
    Investigational

    Zandatrigine is under investigation in clinical trial NCT05226780 (Extension Study to Evaluate How Safe and Tolerable NBI-921352 Is as an Adjunctive Therapy for Participants With SCN8A-DEE).

    Synonyms: Benzenesulfonamide, 2-fluoro-5-methyl-4-(methyl((3s)-1-(phenylmethyl)-3-pyrrolidinyl)amino)-n-4-thiazolyl-
  3. Drug

    (4R)-limonene

    go.drugbank.com/drugs/DB08921
    Investigational

    As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant … in perfumery.

    Synonyms: (R)-4-isopropenyl-1-methyl-1-cyclohexene, (R)-1-methyl-4-(1-methylethenyl)cyclohexene
  4. Drug

    Nesvategrast

    go.drugbank.com/drugs/DB19337
    Investigational

    Nesvategrast is under investigation in clinical trial NCT05409235 (Nesvategrast (OTT166) in Diabetic Retinopathy (DR)).

    Synonyms: (s)-3-(6-(difluoromethoxy)pyridin-3-yl)-3-(oxo-2-3-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl)imidazolidin-1-yl)propanoate, 3-Pyridinepropanoic acid, 6-(difluoromethoxy)-β-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1-imidazolidinyl]-, (βS)-
  5. Drug

    Ceramide NP

    go.drugbank.com/drugs/DB14111
    Investigational

    Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. … Ceramide 3 consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid) [A27233]. It is widely used as a moisturizer in various cosmetic and personal products.

    Synonyms: Cer(t18:0/18:1n-9), N-oloeoyl-4-hydroxysphinganineProducts: Cellapy A Repair, Cellapy A Repair Cream
  6. Drug

    Phosphonotyrosine

    go.drugbank.com/drugs/DB01962
    Experimental

    An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.

  7. Drug

    PF-5212372

    go.drugbank.com/drugs/DB19212
    Investigational

    PF-5212372 is under investigation in clinical trial NCT02795832 (A Study to Determine the Safety & Efficacy of ZPL-5212372 in Healthy Subjects and in Subjects With Atopic Dermatitis).

    Synonyms: Benzenepropanoic acid, 4-((2-(5-chloro-1-(diphenylmethyl)-2-(2-((((2-(trifluoromethyl)phenyl)methyl)sulfonyl)amino)ethyl)-1h-indol-3-yl)ethyl)sulfonyl)-
  8. Drug

    Fursultiamine

    go.drugbank.com/drugs/DB08966
    Approved

    It has also been suggested for several non-deficiency disorders but has not yet proven useful. Fursultiamine is a vitamin B1 derivative.

    International brands: Alinamin FMixtures: ALINAMIN EX PLUS, ALINAMIN-F ODORLESS TABLET
  9. Drug

    Nisevokitug

    go.drugbank.com/drugs/DB17561
    Investigational

    Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety … and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients).

  10. Drug

    Navicixizumab

    go.drugbank.com/drugs/DB12634
    Investigational

    Navicixizumab is under investigation in clinical trial NCT02298387 (A Phase 1 Study of Navicixizumab in Subjects With Solid Tumors).