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Displaying results 8521 - 8530 of 10000 in total
  1. Drug

    Talnetant

    go.drugbank.com/drugs/DB06429
    Investigational

    antipsychotic drug for the treatment of schizophrenia. … Talnetant (SB-223,412) is a neurokinin 3 receptor antagonist developed by GlaxoSmithKline, which is being researched for several different functions, primarily for irritable bowel syndrome and as a potential

  2. Drug

    Latrunculin A

    go.drugbank.com/drugs/DB02621
    Investigational

    Latrunculin A is an actin binding macrolide purified from the red sea sponge Latrunculia magnifica. It is under investigation for the treatment of cancer.

    Synonyms: LAT-A, (+)-latrunculin A
  3. Drug

    Xaliproden

    go.drugbank.com/drugs/DB06393
    Investigational

  4. Drug

    Human interferon omega-1

    go.drugbank.com/drugs/DB05472
    Investigational

    There are multiple routes for administration of omega interferon: injection, an implantable subcutaneous drug delivery system, and an oral formulation. … The biological activities of IFN-omega 1 and its physiological role are not known to date.

  5. Drug

    Mimopezil

    go.drugbank.com/drugs/DB05520
    Experimental

    Mimopezil is an acetylcholinesterase (AChE) inhibitor that has demonstrated potential use in the treatment of Alzheimer's disease. … Mimopezil is a pro-drug that is rapidly absorbed and converted into huperzine A.

    Synonyms: N-(2-Hydroxy-3-methoxy-5-chlorobenzylidene)huperzine A
  6. Drug

    AMG-553

    go.drugbank.com/drugs/DB18346
    Investigational

    AMG-553 is an adoptive, anti-FLT3 chimeric antigen receptor T-cell therapy generated through transduction of autologous T-cells with a self-inactivating human immunodeficiency virus-1 based lentiviral

  7. Drug

    Tersolisib

    go.drugbank.com/drugs/DB21752
    Investigational

    STX-478 is under investigation in clinical trail NCT05768139 (First-in-Human Study of STX-478 as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

  8. Drug

    Human umbilical cord blood mononuclear cell-conditioned medium

    go.drugbank.com/drugs/DB15724
    Experimental

    While some of the positive results are credited to HUCBCs’ differentiation potential, the growth factors and cytokines these cells secrete are also implicated.

  9. Drug

    J147

    go.drugbank.com/drugs/DB13957
    Experimental

    J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. … [A31606,A31607,A31608] It is a curcumin derivative and a potent neurogenic and neuroprotective drug candidate initially developed for the treatment of neurodegenerative conditions associated with aging

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  10. Drug

    BacTRL-spike

    go.drugbank.com/drugs/DB15811
    Investigational

    As of June, 2020, the company is pursuing a Phase 1, Randomized, Observer-Blind, Placebo-Controlled Trial (NCT04334980) to test the safety and immunogenicity of the vaccine. … BacTRL-Spike is composed of a bacterial medium with colony-forming-units of live Bifidobacterium longum engineered to deliver synthetic DNA encoding spike protein from SARS-CoV-2 contained by plasmids.