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Displaying results 8531 - 8540 of 10000 in total
  1. Drug

    Dezapelisib

    go.drugbank.com/drugs/DB16137
    Investigational

    Dezapelisib is under investigation in clinical trial NCT02456675 (INCB040093 and INCB040093 Combined With Itacitinib (INCB039110) in Relapsed/refractory Hodgkin Lymphoma).

    Synonyms: 6-(3-fluorophenyl)-3-methyl-7-[(1S)-1-(7H-purin-6-ylamino)ethyl]-[1,3]thiazolo[3,2-a]pyrimidin-5-one
  2. Drug

    Acetyldinaline

    go.drugbank.com/drugs/DB16142
    Investigational

    Acetyldinaline is under investigation in clinical trial NCT00005624 (CI-994 in Treating Patients With Advanced Myeloma).

  3. Drug

    Eftilagimod alfa

    go.drugbank.com/drugs/DB16150
    Investigational

    Eftilagimod alfa is under investigation in clinical trial NCT02614833 (IMP321 (Eftilagimod Alpha) as Adjunctive to a Standard Chemotherapy Paclitaxel Metastatic Breast Carcinoma).

    Categories: Antigens, Differentiation, T-Lymphocyte, Costimulatory and Inhibitory T-Cell Receptors
  4. Drug

    Efungumab

    go.drugbank.com/drugs/DB16151
    Investigational

    Efungumab is under investigation in clinical trial NCT00217815 (Preliminary Study of Mycograb and Docetaxel in Advanced Breast Cancer).

  5. Drug

    VEGFR2-169

    go.drugbank.com/drugs/DB16152
    Investigational

    VEGFR2-169 is under investigation in clinical trial NCT00655785 (Antiangiogenic Peptide Vaccine Therapy With Gemcitabine in Treating Patient With Pancreatic Cancer (Phase1/2)).

  6. Drug

    Ensifentrine

    go.drugbank.com/drugs/DB16157
    ApprovedInvestigational

    Ensifentrine is a first-in-class, selective dual inhibitor of the phosphodiesterase 3 (PDE3) and phosphodiesterase 4 (PDE4) enzymes.

    Synonyms: 2-(9,10-DIMETHOXY-4-OXO-2-(2,4,6-TRIMETHYLPHENYL)IMINO-6,7-DIHYDROPYRIMIDO(6,1-A)ISOQUINOLIN-3-YL)ETHYLUREA, N-(2-((2E)-9,10-DIMETOXI-4-OXO-2-((2,4,6-TRIMETILFENIL)IMINO)-6,7-DIHIDRO-2H-PIRIMIDO(6,1-A)ISOQUINOLEIN-3(4H)-IL)ETIL)UREACategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  7. Drug

    Tolinapant

    go.drugbank.com/drugs/DB16160
    Investigational

    ASTX660 is under investigation in clinical trial NCT02503423 (Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas).

    Salts: Tolinapant L-(+)-lactic acidCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Fenpyroximate

    go.drugbank.com/drugs/DB16164
    Investigational

    Fenpyroximate is under investigation in clinical trial NCT02533336 (The Effectiveness of Non-pyrethroid Insecticide-treated Durable Wall Liners as a Method for Malaria Control in Endemic Rural Tanzania

    Synonyms: Fenpyroximate (z,e)Categories: Heterocyclic Compounds, 1-Ring, Electron Transport Complex I, antagonists & inhibitors
  9. Drug

    Firsocostat

    go.drugbank.com/drugs/DB16166
    Investigational

    Firsocostat is under investigation in clinical trial NCT02781584 (Safety, Tolerability, and Efficacy of Selonsertib, Firsocostat, and Cilofexor in Adults With Nonalcoholic Steatohepatitis (NASH)).

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Fisogatinib

    go.drugbank.com/drugs/DB16167
    Investigational

    Fisogatinib is under investigation in clinical trial NCT04194801 (A Phase Ib/ii Study of Fisogatinib(blu-554) in Subjects With Hepatocellular Carcinoma).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring