Fisogatinib

DB16167InvestigationalSmall molecule

Fisogatinib is under investigation in clinical trial NCT04194801 (A Phase Ib/ii Study of Fisogatinib(blu-554) in Subjects With Hepatocellular Carcinoma).

Chemical structure of Fisogatinib
Formula / weight
C24H24Cl2N4O4 · 503.38 g/mol (avg)
Code names
BLU-111362 · BLU-554 · X-439161

Resolves to

Compound
UNII5Q7R99CKV2CAS1707289-21-1
Structure
InChIKeyMGZKYOAQVGSSGC-DLBZAZTESA-NSMILESCOC1=CC(OC)=C(Cl)C(=C1Cl)C1=CC2=CN=C(N[C@@H]3COCC[C@@H]3NC(=O)C=C)N=C2C=C1
Targets
P22455FGFR4

What you can answer from here — as of April 23, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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2Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Fisogatinib, and which of those have an active Phase 3 trial?

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