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Mafosfamide
go.drugbank.com/drugs/DB12083InvestigationalMafosfamide has been used in trials studying the treatment of Lymphoma, Leukemia, Meningeal Neoplasm, and Brain and Central Nervous System Tumors.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsTetrahydropalmatine
go.drugbank.com/drugs/DB12093InvestigationalTetrahydropalmatine is under investigation in clinical trial NCT02118610 (Treatment of Schizophrenia With L-tetrahydropalmatine (l-THP): a Novel Dopamine Antagonist With Anti-inflammatory and Antiprotozoal Activity).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPSI-697
go.drugbank.com/drugs/DB12211InvestigationalPSI-697 has been used in trials studying the treatment of Scleritis.
Categories: P-SelectinSeviteronel
go.drugbank.com/drugs/DB12275InvestigationalSeviteronel has been used in trials studying the treatment of CRPC, Prostate Cancer, and Castration-resistant Prostate Cancer.
Categories: Cytochrome P-450 Enzyme InhibitorsSagopilone
go.drugbank.com/drugs/DB12391InvestigationalSagopilone has been used in trials studying the treatment of Melanoma, Neoplasms, CNS Disease, Breast Cancer, and Breast Neoplasms, among others. It is a so-called fully synthetic epothilone and is the first such compound to be in clinic...
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsLobucavir
go.drugbank.com/drugs/DB12531InvestigationalLobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSAR-405838
go.drugbank.com/drugs/DB12541InvestigationalSAR405838 has been used in trials studying the treatment of Neoplasm Malignant.
Categories: P-glycoprotein substratesBucindolol
go.drugbank.com/drugs/DB12752InvestigationalBucindolol has been investigated in Heart Failure.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesGallopamil
go.drugbank.com/drugs/DB12923InvestigationalGallopamil has been used in trials studying the treatment of Asthma.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesCafedrine
go.drugbank.com/drugs/DB12926InvestigationalCafedrine is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates