Search

Displaying results 8541 - 8550 of 10000 in total
  1. Drug

    Fedratinib

    go.drugbank.com/drugs/DB12500
    ApprovedInvestigational

    Fedratinib, also known as SAR302503 and TG101348, is a tyrosine kinase inhibitor used to treat intermediate-2 and high risk primary and secondary myelofibrosis. … [A183176,L8090] It is an anilinopyrimidine derivative.[A183188] Fedratinib was granted FDA approval on August 16, 2019.[L8090]

    Categories: MATE 1 Inhibitors, MATE 2 Inhibitors
  2. Drug

    Atecegatran metoxil

    go.drugbank.com/drugs/DB12507
    Investigational

    Atecegatran metoxil has been used in trials studying the basic science and prevention of Nonvalvular Atrial Fibrillation, Persistent or Permanent Nonvalvular Atrial Fibrillation, and Persistent or Permanent Non-valvular Atrial Fibrillation.

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Imiglitazar

    go.drugbank.com/drugs/DB12511
    Investigational

    Imiglitazar has been used in trials studying the treatment of Diabetes Mellitus.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Verucerfont

    go.drugbank.com/drugs/DB12512
    Investigational

    Verucerfont has been used in trials studying the treatment of Congenital Adrenal Hyperplasia.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Omaveloxolone

    go.drugbank.com/drugs/DB12513
    ApprovedInvestigational

    [A257534,A257539] Omaveloxolone acts as an activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), a transcription factor that mitigates oxidative stress. … In patients with Friedreich's ataxia, a genetic disease involving mitochondrial dysfunction, the Nrf2 pathway is impaired, and Nrf2 activity is lower.

    Categories: Cytochrome P-450 CYP2C8 Inducers, Cytochrome P-450 SubstratesSynonyms: Propanamide, N-(2-cyano-3,12-dioxo-28-noroleana-1,9(11)-dien-17-yl)-2,2-difluoro-
  6. Drug

    Iofolastat I-123

    go.drugbank.com/drugs/DB12514
    Investigational

    Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer).

    Synonyms: Iofolastat i 123, Iofolastat (123 I)
  7. Drug

    BI-671800

    go.drugbank.com/drugs/DB12524
    Investigational

    Bi 671800 has been used in trials studying the treatment of Asthma and Rhinitis, Allergic, Perennial.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Batefenterol

    go.drugbank.com/drugs/DB12526
    Investigational

    Batefenterol has been used in trials studying the treatment of Pulmonary Disease, Chronic Obstructive.

    Categories: Heterocyclic Compounds, 2-Ring, Adrenergic beta-2 Receptor Agonists
  9. Drug

    Lobucavir

    go.drugbank.com/drugs/DB12531
    Investigational

    Lobucavir has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  10. Drug

    N-acetylmannosamine

    go.drugbank.com/drugs/DB12536
    Investigational

    N-acetylmannosamine is under investigation for the other of GNE Myopathy.

    Synonyms: N-acetylmannosamine