Iofolastat I-123

DB12514InvestigationalSmall molecule

Iofolastat I-123 is under investigation in clinical trial NCT00992745 (A Phase I Pilot Study Comparing 123I MIP 1072 Versus 111In Capromab Pendetide in Subjects With Metastatic Prostate Cancer).

Chemical structure of Iofolastat I-123
Formula / weight
C19H26IN3O7 · 531.337 g/mol (avg)
Also known as
Iofolastat (123 I) · Iofolastat i 123
Code names
123-I-MIP-1072 · MIP-1072

Resolves to

Compound
UNIIAQF0A29T2VCAS949575-24-0ChEMBLCHEMBL496978PubChem25194767
Structure
InChIKeyOXUUJYOSVPMNKP-ZANJDRPYSA-NSMILESOC(=O)CC[C@H](NC(=O)N[C@@H](CCCCNCC1=CC=C([123I])C=C1)C(O)=O)C(O)=O
Targets
Q04609FOLH1

What you can answer from here — as of October 29, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
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2Clinical trialsPhase, status and sponsor resolved per trial
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1+ReferenceStructured and connected to the statements they support
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Which drugs share a target with Iofolastat I-123, and which of those have an active Phase 3 trial?

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