This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Generic Name
- N-acetylmannosamine
- DrugBank Accession Number
- DB12536
- Background
N-acetylmannosamine is under investigation for the other of GNE Myopathy.
- Type
- Small Molecule
- Groups
- Investigational
- Structure
Structure for N-acetylmannosamine (DB12536)
- Weight
- Average: 221.2078
Monoisotopic: 221.089937217 - Chemical Formula
- C8H15NO6
- Synonyms
- MANNAC
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity.
- Kingdom
- Organic compounds
- Super Class
- Organic oxygen compounds
- Class
- Organooxygen compounds
- Sub Class
- Carbohydrates and carbohydrate conjugates
- Direct Parent
- Hexoses
- Alternative Parents
- Aminosaccharides / Beta-hydroxy aldehydes / Acetamides / Secondary carboxylic acid amides / Secondary alcohols / Polyols / Primary alcohols / Organopnictogen compounds / Organonitrogen compounds / Organic oxides show 1 more
- Substituents
- Acetamide / Alcohol / Aldehyde / Aliphatic acyclic compound / Amino saccharide / Beta-hydroxy aldehyde / Carbonyl group / Carboxamide group / Carboxylic acid derivative / Hexose monosaccharide show 9 more
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- X80PR7P73R
- CAS number
- 3615-17-6
- InChI Key
- MBLBDJOUHNCFQT-WCTZXXKLSA-N
- InChI
- InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6-,7-,8-/m1/s1
- IUPAC Name
- N-[(2S,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide
- SMILES
- [H][C@@](O)(CO)[C@@]([H])(O)[C@]([H])(O)[C@]([H])(NC(C)=O)C=O
References
- General References
- Not Available
- External Links
- Human Metabolome Database
- HMDB0062500
- PubChem Compound
- 65150
- PubChem Substance
- 347828762
- ChemSpider
- 58659
- ChEBI
- 17122
- ZINC
- ZINC000002020190
- PDBe Ligand
- MN9
- Wikipedia
- N-Acetylmannosamine
- PDB Entries
- 4bwl / 4woz / 6ppz
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data2 Active Not Recruiting Treatment GNE Myopathy 1 somestatus stop reason just information to hide 2 Completed Treatment GNE Myopathy 1 somestatus stop reason just information to hide 2 Not Yet Recruiting Treatment Focal Segmental Glomerulosclerosis (FSGS) 1 somestatus stop reason just information to hide 1 Completed Treatment GNE Myopathy 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 148.0 mg/mL ALOGPS logP -2.1 ALOGPS logP -3.9 Chemaxon logS -0.18 ALOGPS pKa (Strongest Acidic) 12.09 Chemaxon pKa (Strongest Basic) -1.8 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 5 Chemaxon Polar Surface Area 127.09 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 48.45 m3·mol-1 Chemaxon Polarizability 20.73 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 151.1130534 predictedDarkChem Lite v0.1.0 [M-H]- 152.79079 predictedDeepCCS 1.0 (2019) [M+H]+ 149.8162534 predictedDarkChem Lite v0.1.0 [M+H]+ 155.18658 predictedDeepCCS 1.0 (2019) [M+Na]+ 149.3017534 predictedDarkChem Lite v0.1.0 [M+Na]+ 161.63667 predictedDeepCCS 1.0 (2019)
Drug created at October 20, 2016 22:45 / Updated at June 12, 2020 16:53