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BMS-791826
go.drugbank.com/drugs/DB15023InvestigationalBMS-791826 is under investigation in clinical trial NCT03198013 (A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy Males).
Categories: Heterocyclic Compounds, 1-RingR-30490
go.drugbank.com/drugs/DB09179ExperimentalR-30490 was found to be the most selective agonist for the mu opioid receptor out of all the fentanyl analogues tested, but it has never been introduced for medical use in humans, although the closely … R-30490 is an opioid related to carfentanil used as an animal tranquilizer.
Categories: Heterocyclic Compounds, 1-RingRocapuldencel-T
go.drugbank.com/drugs/DB17588InvestigationalRocapuldencel-T is an autologous dendritic cell immunotherapy that was investigated in NCT02662634 (A Safety and Feasibility Study of AGS-003-LNG for the Treatment of Stage 3 Non Small Cell Lung Cancer
Synonyms: Rocapuldencel-TST-36
go.drugbank.com/drugs/DB17275ExperimentalST-36 is a cell-penetrating dominant-negative form of activating transcription factor 5. In 2017, it received orphan drug designation by the FDA for the treatment of glioma.[L47341]
HMI-203
go.drugbank.com/drugs/DB18520InvestigationalIt consists of a recombinant adeno-associated virus (AAV) serotype HSC15 (rAAVHSC15) encoding human iduronate-2-sulfatase (hIDS). … HMI-203 is an investigational gene therapy developed by Homology Medicines, Inc.
Tramazoline
go.drugbank.com/drugs/DB13064InvestigationalTramazoline is under investigation in clinical trial NCT01601509 (Nasal Tramazoline and Dexamethazone in Obstructive Sleep Apnea (OSA) Patients Tramazoline and).
Categories: Heterocyclic Compounds, 1-Ringnor-NOHA
go.drugbank.com/drugs/DB02381InvestigationalN-Hydroxy-nor-L-arginine (nor-NOHA) is under investigation in clinical trial NCT02009527 (Arginase Inhibition in Ischemia-reperfusion Injury).
Synonyms: N-hydroxy-nor-L-arginine, N-hydroxy-nor-arginineMK-0752
go.drugbank.com/drugs/DB12852InvestigationalMk 0752 is under investigation in clinical trial NCT00572182 (MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer).
Caficrestat
go.drugbank.com/drugs/DB15121InvestigationalAT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingLenzilumab
go.drugbank.com/drugs/DB15148InvestigationalLenzilumab is under investigation in clinical trial NCT02546284 (Study of Lenzilumab in Previously Treated Patients With Chronic Myelomonocytic Leukemia (CMML)).