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Cardiolipin Biosynthesis CL(8:0/i-24:0/25:0/25:0)
smpdb.ca/view/SMP0491942MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Cardiolipin Biosynthesis CL(13:0/13:0/i-19:0/24:0)
smpdb.ca/view/SMP0495579MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Diiodohydroxyquinoline
go.drugbank.com/drugs/DB09115ApprovedIodoquinol is not currently available in any FDA-approved products. … Diiodohydroxyquinoline, also known as uidoquinol and iodoquinol, is a quinoline derivative that can be used in the treatment of amoebiasis. The exact mechanism of action is unknown.
Mixtures: GYNECON - T, NORECIL 600Categories: Heterocyclic Compounds, 2-RingSegesterone acetate
go.drugbank.com/drugs/DB14583ApprovedOn August 10, 2018, Annovera™ containing segesterone acetate and [ethinyl estradiol] was granted approval by the U.S. … In animal studies, segesterone acetate was shown to be one of the most potent progestins [A37090]. It mediates progestational activity 100 times higher than that of [progesterone] [A37092].
Synonyms: 17-Hydroxy-16-methylene-19-norpregn-4-ene-3,20-dione acetate, 16-Methylene-17-alpha-acetoxy-19-nor-4-pregnene-3,20-dioneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBamlanivimab
go.drugbank.com/drugs/DB15718ApprovedInvestigational[L20979] Based on phase 2 clinical trial (BLAZE-1) interim results, bamlanivimab was granted Emergency Use Authorization (EUA) by the FDA on November 10, 2020. … it in collaboration with Eli Lilly and Company.
Tixagevimab
go.drugbank.com/drugs/DB16394ApprovedInvestigationalTixagevimab, in combination with [cilgavimab], was issued an FDA emergency use authorization (EUA) on December 9, 2021, for the pre-exposure prophylaxis of COVID-19 in individuals at increased risk for … [L39411] EVUSHELD was granted marketing authorization by the EMA on March 28, 2022,[L41454] and was approved in Canada soon after, on April 14, 2022.
Lumefantrine
go.drugbank.com/drugs/DB06708ApprovedInvestigationalLumefantrine is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. … </i> and may be used to treat infections caused by <i>P. falciparum</i> and unidentified <i>Plasmodium</i> species, including infections acquired in chloroquine-resistant areas.
Mixtures: Riamet 20 mg/120 mg - Tabletten, ARTEMETERO 20 MG + LUMEFANTRINA 120 MG TABLETACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsCyclizine
go.drugbank.com/drugs/DB01176ApprovedWithdrawnA histamine H1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (From Martindale, The Extra Pharmacopoeia, 30th ed, p935)
Categories: Cytochrome P-450 CYP2C9 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: 1-Benzhydryl-4-methylpiperazin, (±)-1-diphenylmethyl-4-methylpiperazineCytisine
go.drugbank.com/drugs/DB09028InvestigationalCytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum and Cytisus. … Recent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement therapy.
Categories: Heterocyclic Compounds, 2-Ring, Drugs Used in Addictive DisordersSynonyms: (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido[1,2a][1,5]diazocin-8-oneCardiolipin Biosynthesis CL(10:0/18:2(9Z,11Z)/a-21:0/i-24:0)
smpdb.ca/view/SMP0178821MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...