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Oxypurinol
go.drugbank.com/drugs/DB05262InvestigationalOxypurinol, an inhibitor of xanthine oxidase, is a metabolite of allopurinol.
Synonyms: 1H-Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dioneCategories: Heterocyclic Compounds, 1-RingiCo-007
go.drugbank.com/drugs/DB05268InvestigationaliCo-007 (formerly known as ISIS 13650) is a second generation antisense compound being developed by iCo for the treatment of various eye diseases caused by the formation of new blood vessels (angiogenesis
SB-249553
go.drugbank.com/drugs/DB05285ExperimentalSB-249553 is a vaccine that has MAGE-3 cancer antigen and the Adjuvant SBAS-2. It is also under by GlaxoSmithKline to treat melanoma and lung cancer.
Eldecalcitol
go.drugbank.com/drugs/DB05295InvestigationalEldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis.
Synonyms: 1α,25-dihydroxy-2β-(3-hydroxypropoxy)cholecalciferolCategories: Vitamin D and AnaloguesTetomilast
go.drugbank.com/drugs/DB05298InvestigationalTetomilast has been used in trials studying the treatment of Crohn Disease, Colitis, Ulcerative, and Chronic Obstructive Pulmonary Disease.
Categories: Heterocyclic Compounds, 1-RingOMS-103HP
go.drugbank.com/drugs/DB05303InvestigationalOMS103HP is the first drug being developed to improve joint function following arthroscopic surgery, one of the most common procedures performed today by orthopedic surgeons.
Categories: Heterocyclic Compounds, 1-RingAlferminogene tadenovec
go.drugbank.com/drugs/DB05306InvestigationalAlferminogene tadenovec represents a new therapeutic class of biologics designed to promote angiogenesis and thereby improve blood flow following a one-time intracoronary administration from a standard
Synonyms: Ad5FGF-4Folitixorin calcium
go.drugbank.com/drugs/DB05308InvestigationalANX-510 (CoFactor) is a folate-based biomodulator drug being developed to enhance the activity and reduce associated toxicity of the widely used cancer chemotherapy, 5-fluorouracil (5-FU). … CoFactor use with 5-FU is being evaluated in clinical trials in first line treatment of metastatic colorectal cancer.
Ecallantide
go.drugbank.com/drugs/DB05311ApprovedBy reversibly binding to plasma kallikrein, ecallantide displays a rapid on-rate and a slow off-rate that results in high affinity inhibition in the picomolar range [L1458]. … Ecallantide is a potent and selective human plasma kallikrein inhibitor that is indicated for the symptomatic treatment of hereditary angioedema.
Products: KALBITOR® 10 MG / MLMC-1
go.drugbank.com/drugs/DB05315ExperimentalMedicure's MC-1 drug is a cardio-protectant, designed to reduce the damage to the heart when arteries are blocked and when they are subsequently reopened after bypass surgery.
Synonyms: MC-1