Search

Displaying results 8571 - 8580 of 10000 in total
  1. Drug

    1,2-Benzodiazepine

    go.drugbank.com/drugs/DB12537
    ApprovedInvestigationalWithdrawn

    Benzodiazepine is under investigation for the prevention of Delirium and C.Surgical Procedure; Cardiac. Benzodiazepine has been investigated for the treatment of Obesity, Sleep Apnea, Obstructive, and Disorders of Gallbladder, Biliary Tr...

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  2. Drug

    Samidorphan

    go.drugbank.com/drugs/DB12543
    ApprovedInvestigational

    [A235638, A235643] Samidorphan is a novel opioid antagonist structurally related to [naltrexone], with a higher affinity for opioid receptors, more potent μ-opioid receptor antagonism, higher oral bioavailability … , and a longer half-life, making it an attractive candidate for oral dosing.

    Salts: Samidorphan L-malateCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  3. Drug

    Indobufen

    go.drugbank.com/drugs/DB12545
    Investigational

    Indobufen has been used in trials studying the supportive care and prevention of Atrial Fibrillation.

    Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-RingProducts: INDOBUFENE EG
  4. Drug

    Sparsentan

    go.drugbank.com/drugs/DB12548
    ApprovedInvestigational

    Sparsentan is a dual antagonist of the endothelin type A receptor (ET<sub>A</sub>R) and the angiotensin II (Ang II) type 1 receptor (AT<sub>1</sub>R) with a similar affinity for both (9.3 nM for ET<sub … >A</sub>R antagonist.

    Categories: Dual Endothelin Type A Receptor/Ang II Subtype 1 Receptor Antagonist (DEARA), Angiotensin 2 Receptor Blocker
  5. Drug

    Taladegib

    go.drugbank.com/drugs/DB12550
    Investigational

    Taladegib has been used in trials studying the treatment of Solid Tumor, COLON CANCER, BREAST CANCER, Advanced Cancer, and Rhabdomyosarcoma, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Idazoxan

    go.drugbank.com/drugs/DB12551
    Investigational

    Idazoxan has been used in trials studying the basic science of Molecular Imaging, Alzheimer Disease, and Major Depressive Disorder.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  7. Drug

    MK-5108

    go.drugbank.com/drugs/DB12556
    Investigational

    MK-5108 has been used in trials studying the treatment of Cancer, Neoplasms, Tumors.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Camicinal

    go.drugbank.com/drugs/DB12567
    Investigational

    Camicinal has been used in trials studying the treatment of Gastroparesis.

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Tonapofylline

    go.drugbank.com/drugs/DB12569
    Investigational

    Tonapofylline has been used in trials studying the treatment of Heart Failure, Renal Insufficiency, and Congestive Heart Failure.

    Categories: Heterocyclic Compounds, 2-Ring
  10. Drug

    Onatasertib

    go.drugbank.com/drugs/DB12570
    Investigational

    Onatasertib (CC-223) has been used in trials studying the treatment and basic science of Multiple Myeloma, Glioblastoma Multiforme, HepatoCellular Carcinoma, Non-small Cell Lung Cancer, and Diffuse Large B-Cell

    Categories: Heterocyclic Compounds, 1-Ring