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Displaying results 851 - 860 of 1203 in total
  1. Drug

    Dihydroergotamine

    go.drugbank.com/drugs/DB00320
    ApprovedInvestigational

    Recent improvements have been made in the design of intranasal delivery devices allowing for greater delivery of dihydroergotamine solution to the vasculature-rich upper nasal cavity.

    Categories: Serotonin Receptor Agonists, Adrenergic alpha-1 Receptor Antagonists
  2. Indication

    Anticholinergic Syndrome

    go.drugbank.com/conditions/DBCOND0005987
    Drugs: Physostigmine
    Synonyms: Poisoning caused by acetylcholine receptor antagonist, Poisoning caused by acetylcholine receptor antagonist (disorder)
  3. Drug

    Pemivibart

    go.drugbank.com/drugs/DB18720
    Investigational

    Pemivibart (Pemgarda) is a human IgG1 monoclonal antibody targeting the SARS-CoV-2 spike protein receptor binding domain.

  4. Drug

    Afamelanotide

    go.drugbank.com/drugs/DB04931
    Approved

    [L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125]

    Categories: Melanocortin Receptor Agonists, Melanocortin 1 Receptor (MC1-R) Agonists
  5. Drug

    Metformin

    go.drugbank.com/drugs/DB00331
    ApprovedInvestigational

    Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes. Metformin is considered an antihyperglycemic drug because it lowers blood glucose concentrations in type II diabe...

  6. Drug

    Fidanacogene elaparvovec

    go.drugbank.com/drugs/DB16783
    ApprovedInvestigational

    [L49469] This approval was based on positive results demonstrated in the open-label, single-arm Phase 3 BENEGENE-2 study, where the annualized bleeding rate (ABR) was observed to be 1.3 for the 12 months

  7. Drug

    Diethylamino hydroxybenzoyl hexyl benzoate

    go.drugbank.com/drugs/DB11269
    Approved

    Diethylamino hydroxybenzoyl hexyl benzoate is a UV filter with high absorption in the UV-A range. Minimizing the overexposure of human skin to ultraviolet radiation that may lead to acute and chronic photodamage, diethylamino hydroxybenz...

    Mixtures: Wonder Intensive BBCream 21 (Light)
  8. Drug

    Arbutin

    go.drugbank.com/drugs/DB11217
    Approved

    Extracted from the dried leaves of bearberry plant in the genus Arctostaphylos and other plants commonly in the Ericaceae family, arbutin is a beta-D-glucopyranoside of DB09526. It is found in foods, over-the-counter drugs, and herbal di...

    Mixtures: Wonder Intensive BBCream 21 (Light)
  9. Drug

    Phenserine

    go.drugbank.com/drugs/DB04892
    Investigational

    If this is substantiated in an ongoing clinical trial then phenserine may open the door to an entirely new type of treatment for AD.

  10. Drug

    Picrotoxin

    go.drugbank.com/drugs/DB00466
    Experimental

    A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the gamma-aminobutyric acid-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and...

    Categories: GABA-A Receptor Antagonists