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Displaying results 8621 - 8630 of 10000 in total
  1. Drug

    Temuterkib

    go.drugbank.com/drugs/DB18806
    Investigational

    Synonyms: 4h-thieno(2,3-c)pyrrol-4-one, 5,6-dihydro-6,6-dimethyl-2-(2-((1-methyl-1h-pyrazol-5-yl)amino)-4-pyrimidinyl)-5-(2-(4-morpholinyl)ethyl)-, 5,6-dihydro-6,6-dimethyl-2-(2-((1-methyl-1h-pyrazol-5-yl)amino)-4-pyrimidinyl)-5-(2-(4-morpholinyl)ethyl)-4h-thieno(2,3-c)pyrrol-4-oneCategories: Heterocyclic Compounds, 1-Ring
  2. Drug

    TAS-303

    go.drugbank.com/drugs/DB18808
    Investigational

    Synonyms: 4-PIPERIDINYL .ALPHA.-PHENYL-.ALPHA.-(PROPOXY-1,1,2,2,3,3,3-D7)BENZENEACETATECategories: Heterocyclic Compounds, 1-Ring
  3. Drug

    Rocatinlimab

    go.drugbank.com/drugs/DB18809
    Investigational

    Rocatinlimab is a subcutaneously administered anti-OX40 antibody developed for the treatment of moderate-to-severe atopic dermatitis. … Despite its promising results, the long-term safety of rocatinlimab requires further investigation, as serious adverse events and injection reactions such as fever and chills have been reported.

  4. Drug

    ABG-023

    go.drugbank.com/drugs/DB18829
    Experimental

    ABG-023 is a glucagon analog which is soluble and solution-stable.[L50778]

  5. Drug

    Ziltivekimab

    go.drugbank.com/drugs/DB18836
    Investigational

    Ziltivekimab is under investigation in clinical trial NCT06200207 (A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation).

    Synonyms: Immunoglobulin g1 (255-tyrosine,257-threonine,259-glutamic acid), anti-(human interleukin 6) (human monoclonal 2e2.3a9.6a3 .gamma.1-chain), disulfide with human monoclonal 2e2.3a9.6a3 .kappa.
  6. Drug

    Allitinib

    go.drugbank.com/drugs/DB18840
    Experimental

    Allitinib is under investigation in clinical trial NCT04671303 (To Evaluate the Efficacy and Safety of Anlotinib Combined With Allitinib in Lung Cancer).

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-propenamide, n-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-, N-(4-((3-chloro-4-((3-fluorophenyl)methoxy)phenyl)amino)-6-quinazolinyl)-2-propenamide
  7. Drug

    Socazolimab

    go.drugbank.com/drugs/DB18845
    Investigational

    Socazolimab is under investigation in clinical trial NCT04878016 (A Study of Carboplatin Plus Etoposide With or Without ZKAB001 (Anti-pd-l1 Antibody) in Patients With ES-SCLC).

    Synonyms: Immunoglobulin g1, anti-(human programmed death-ligand 1) (human monoclonal zkab001 .gamma.1-chain), disulfide with human monoclonal zkab001 .lambda.-chain, dimer
  8. Drug

    Depemokimab

    go.drugbank.com/drugs/DB18846
    ApprovedInvestigational

    Depemokimab is a humanized Immunoglobulin G1 (IgG1) monoclonal antibody and a long-acting drug. … [A275338] Depemokimab blocks interleukin-5 (IL-5), a key cytokine that regulates eosinophil maturation, survival, and recruitment.

    Categories: Interleukin-5 AntagonistSynonyms: Immunoglobulin g1, anti-(human interleukin 5) (human-mus musculus monoclonal gsk3511294 .gamma.1-chain), disulfide with human-mus musculus monoclonal gsk3511294 .kappa.-chain, dimer
  9. Drug

    Deuruxolitinib

    go.drugbank.com/drugs/DB18847
    ApprovedInvestigational

    Deuruxolitinib is a deuterated form of [ruxolitinib] that selectively inhibits Janus kinases (JAK) JAK1 and JAK2. … [L51083] Alopecia areata is an autoimmune condition that attacks the hair follicles and leads to unpredictable hair loss in the scalp and other areas of the body.

    Categories: MATE 2 Inhibitors, P-glycoprotein substratesSynonyms: (3r)-3-(2,2,3,3,4,4,5,5-d8)cyclopentyl-3-(4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-1h-pyrazol-1-yl)propanenitrile, 1h-pyrazole-1-propanenitrile, .beta.-(cyclopentyl-2,2,3,3,4,4,5,5-d8)-4-(7h-pyrrolo(2,3-d)pyrimidin-4-yl)-, (.beta.r)-
  10. Drug

    Rosnilimab

    go.drugbank.com/drugs/DB18851
    Investigational

    Rosnilimab is under investigation in clinical trial NCT06041269 (A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)).

    Synonyms: Immunoglobulin g1, anti-(human programmed cell death protein 1) (human-mus musculus monoclonal anb030 .gamma.1-chain), disulfide with human-mus musculus monoclonal anb030 .kappa.-chain, dimer