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MOL-4239
go.drugbank.com/drugs/DB16051InvestigationalMOL-4239 is under investigation in clinical trial NCT01826201 (Paired Psoriasis Lesion, Comparative, Study to Evaluate MOL4239 in Psoriasis).
GTB-3550
go.drugbank.com/drugs/DB18494InvestigationalGTB-3550 is a single-chain, tri-specific scFv recombinant fusion protein conjugate composed of the variable regions of the heavy and light chains of anti-CD16 and anti-CD33 antibodies and a modified form … of Interleukin 15 (IL-15).
Synonyms: single chain recombinant trispecific killer engager consistent of anti-CD16 scFV spliced to anti-CD33 scFV with a modified IL-15 linkerCoumazoline
go.drugbank.com/drugs/DB21226ExperimentalCoumazoline is a small molecule drug. The usage of the INN stem '-azoline' in the name indicates that Coumazoline is a antihistaminic or local vasoconstrictor, antazoline derivative.
Domazoline
go.drugbank.com/drugs/DB19937ExperimentalDomazoline is a small molecule drug. The usage of the INN stem '-azoline' in the name indicates that Domazoline is a antihistaminic or local vasoconstrictor, antazoline derivative.
Formic acid
go.drugbank.com/drugs/DB01942ApprovedInvestigationalIt is an important intermediate in chemical synthesis and occurs naturally, most famously in the venom of bee and ant stings. … It is commonly used as a preservative and antibacterial agent in livestock feed.
Ninvosudil
go.drugbank.com/drugs/DB08756InvestigationalY-27632 is an inhibitor of Rho-associated protein kinase. It inhibits calcium sensitization to affect smooth muscle relaxation.
Synonyms: (R)-(+)-trans-N-(4-pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamideSNX-5422
go.drugbank.com/drugs/DB06070InvestigationalSNX-5422 is a synthetic, novel, small molecule Hsp90 Inhibitor. … As an oral formulation that demonstrates strong efficacy and tolerability, SNX-5422 is positioned as a breakthrough therapy with broad applicability across a wide range of cancers.
Milademetan
go.drugbank.com/drugs/DB15257InvestigationalMilademetan is under investigation in clinical trial NCT02319369 (Safety, Tolerability and Pharmacokinetics of Milademetan Alone and With 5-Azacitidine (AZA) in Acute Myelogenous Leukemia (AML) or High-Risk
Urolithin A
go.drugbank.com/drugs/DB15464ExperimentalUrolithin A is a metabolite of ellagic acid. It has been demonstrated to stimulate mitophagy and improve muscle health in old animals and in preclinical models of aging.[A179494]
Deutarserine
go.drugbank.com/drugs/DB19057InvestigationalDeutarserine is under investigation in clinical trial NCT04158687 (A Phase 2 Study to Evaluate the Safety and Efficacy of CTP-692 as an Adjunctive Treatment in Adults With Schizophrenia).