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Displaying results 8651 - 8660 of 10000 in total
  1. Drug

    Donidalorsen

    go.drugbank.com/drugs/DB18751
    ApprovedInvestigational

    Hereditary angioedema (HAE) is a rare genetic disease characterized by recurrent episodes of severe swelling induced by excessive production of bradykinin. … [A274308] Donidalorsen is a ligand-conjugated antisense oligonucleotide that reduces plasma prekallikrein production, thereby reducing bradykinin production and preventing the initiation of attacks.

    Synonyms: -(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL), DNA, D((2'-O-(2-METHOXYETHYL))M5RU-SP-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RA-SP-G-SP-T-SP-M5C-SP-T-SP-M5C-SP-T-SP-T-SP-G-SP-G-SP-M5C-SP
  2. Drug

    Diaminopyrimidine oxide

    go.drugbank.com/drugs/DB18756
    Approved

    Diaminopyrimidine oxide is a compound similar to [minoxidil] which is used to aid in hair growth.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2,4-diaminopyrimidine 3-n-oxide, 2,4-pyrimidinediamine, 3-oxide
  3. Drug

    CL-315585

    go.drugbank.com/drugs/DB18758
    Experimental

    CL-315585 is the D isomer of [Verteporfin].

    Synonyms: Bpd-ma(sub d), 23h,25h-benzo(b)porphine-9,13-dipropanoic acid, 18-ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-, .alpha.13-methyl ester, trans-
  4. Drug

    Sacituzumab tirumotecan

    go.drugbank.com/drugs/DB18777
    Investigational

    Sacituzumab tirumotecan is a recombinant humanized IgG1 anti-TROP2 monoclonal antibody conjugated to a topoisomerase I inhibitor.

  5. Drug

    Ulonivirine

    go.drugbank.com/drugs/DB18787
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Ulixacaltamide

    go.drugbank.com/drugs/DB18788
    Investigational

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Traxoprodil

    go.drugbank.com/drugs/DB18795
    Investigational

    Synonyms: 1-piperidineethanol, 4-hydroxy-.alpha.-(4-hydroxyphenyl)-.beta.-methyl-4-phenyl-, (s-(r*,r*))-, (.alpha.s,.beta.s)-4-hydroxy-.alpha.-(p-hydroxyphenyl)-.beta.-methyl-4-phenyl-1-piperidineethanolCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Sivopixant

    go.drugbank.com/drugs/DB18816
    Investigational

    Synonyms: 1,3,5-triazine-1(2h)-propanoic acid, 3-((4-chlorophenyl)methyl)tetrahydro-.alpha.-methyl-2,6-dioxo-4-((4-(2-pyridinyloxy)phenyl)imino)-, (.alpha.s,4e)-Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Amlitelimab

    go.drugbank.com/drugs/DB18835
    Investigational

    Amlitelimab is under investigation in clinical trial NCT06181435 (A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years … and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)).

    Synonyms: Immunoglobulin g4 (235-proline,242-glutamic acid), anti-(human ox40 ligand) (human monoclonal ky1005-2d10 .gamma.4-chain), disulfide with human monoclonal ky1005-2d10 .kappa.-chain, dimer
  10. Drug

    Befotertinib

    go.drugbank.com/drugs/DB18844
    Investigational

    Befotertinib is under investigation in clinical trial NCT05007938 (Befotertinib and Icotinib in Treatment-naive Patients With Advanced Egfr-mutant Lung Cancer).

    Synonyms: 2-propenamide, n-(2-((2-(dimethylamino)ethyl)methylamino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1h-indol-3-yl)-2-pyrimidinyl)amino)phenyl)-, N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-(2,2,2-trifluoroethyl)-1h-indol-3-yl)pyrimidin-2-yl)amino)phenyl)prop-2-enamideCategories: P-glycoprotein inhibitors