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Eplontersen
go.drugbank.com/drugs/DB16199ApprovedInvestigationalIt was previously investigated as a potential treatment for hereditary transthyretin-mediated amyloidosis. … [A262985] As eplontersen targets both the WT and mutant TTR, it poses tremendous promises as a treatment.
Bepirovirsen
go.drugbank.com/drugs/DB16202InvestigationalIONIS-HBVRx is under investigation in clinical trial NCT04544956 (A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B).
Ivuxolimab
go.drugbank.com/drugs/DB16208InvestigationalIvuxolimab is under investigation in clinical trial NCT02554812 (A Study of Avelumab in Combination With Other Cancer Immunotherapies in Advanced Malignancies (JAVELIN Medley)).
Apinocaltamide
go.drugbank.com/drugs/DB16241InvestigationalApinocaltamide is under investigation in clinical trial NCT03239691 (A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients).
MK-0773
go.drugbank.com/drugs/DB16244InvestigationalMK-0773 is under investigation in clinical trial NCT00529659 (A Study of the Safety and Efficacy of MK-0773 in Women With Sarcopenia (Loss of Muscle Mass)(mk-0773-005)).
Olvimulogene nanivacirepvec
go.drugbank.com/drugs/DB16268InvestigationalOlvimulogene nanivacirepvec is under investigation in clinical trial NCT01443260 (A Study of GL-ONC1, an Oncolytic Vaccinia Virus, in Patients With Advanced Peritoneal Carcinomatosis).
Osoresnontrine
go.drugbank.com/drugs/DB16274InvestigationalOsoresnontrine is under investigation in clinical trial NCT02281773 (A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12 Weeks
Pegylated Recombinant Human Arginase I
go.drugbank.com/drugs/DB16282InvestigationalPegylated Recombinant Human Arginase I is under investigation in clinical trial NCT03455140 (A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100)).
Perfluorodecalin
go.drugbank.com/drugs/DB16292Investigationalinvestigation in clinical trial NCT03668665 (Influencing Wound Healing Through the Application of Hyaluronic Acid With Perfluorodecalin and Physalis Angulata Extract After Split Skin Removal From the Thigh - a
Synonyms: Fluosol da perfluorodecalinRacemetyrosine
go.drugbank.com/drugs/DB16306InvestigationalRacemetyrosine is under investigation in clinical trial NCT03512756 (A Randomized Phase 2/3 Multi-center Study of SM-88 in Patients With Metastatic Pancreatic Cancer).
Synonyms: D,L-metyrosine