Search

Displaying results 8661 - 8670 of 10000 in total
  1. Drug

    ssCART-19 cells

    go.drugbank.com/drugs/DB18653
    Investigational

    ssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6).

    Synonyms: autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6) (also termed ssCART-19 cells)
  2. Drug

    Suratadenoturev

    go.drugbank.com/drugs/DB18672
    Investigational

    Suratadenoturev is a gene-modified oncolytic adenovirus expressing the telomerase reverse transcriptase gene.

    Synonyms: A recombinant replication-competent adenovirus type 5 (Ad-5) in which the E1 gene, including its normal transcriptional regulatory element, has been deleted and replaced by an expression cassette containing, an hTERT (human telomerase reverse transcriptas
  3. Drug

    XEN-D0501

    go.drugbank.com/drugs/DB18673
    Investigational

    XEN-D0501 is a tetrahydronaphthyl urea-based selective TRPV1 antagonist being investigated for the treatment of erythromelalgia.

  4. Drug

    EDIT-101

    go.drugbank.com/drugs/DB18687
    Investigational

    EDIT-101 is a recombinant adeno-associated virus pseudotyped with serotype 5 viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein 9) gene editing

    Synonyms: a recombinant adeno-associated virus pseudotyped with serotype 5 viral capsid encoding CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats associated protein 9) gene editing constructs
  5. Drug

    rAAV1-CB-hAAT

    go.drugbank.com/drugs/DB18724
    Investigational

    rAAV1-CB-hAAT is a recombinant adeno-associated virus alpha 1-antitrypsin vector.

  6. Drug

    CN-201

    go.drugbank.com/drugs/DB18726
    Investigational

    CN-201 is a humanized anti-CD3/CD19 bispecific antibody.

  7. Drug

    HH-009

    go.drugbank.com/drugs/DB18727
    Investigational

    HH-009 is a recombinant human IgG4 monoclonal antibody against FGF19 being studied for the treatment of hepatocellular carcinoma.

  8. Drug

    Calpurbatug

    go.drugbank.com/drugs/DB18734
    Investigational

    Calpurbatug (TRL1068) is a high-affinity and broad-spectrum human antibody that targets and disintegrates bacterial biofilm.

  9. Drug

    APL-030

    go.drugbank.com/drugs/DB18735
    Experimental

    APL-030 is a orally-active small molecule inhibitor of GCN2.

  10. Drug

    Celastrol

    go.drugbank.com/drugs/DB18736
    Experimental

    Celastrol is a pentacyclic triterpenoid isolated from the root extracts of _Tripterygium wilfordii_.[L50567]