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Etidocaine
go.drugbank.com/drugs/DB08987ApprovedEtidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.
Eprazinone
go.drugbank.com/drugs/DB08990ApprovedWithdrawnEprazinone (trade name Eftapan) is a mucolytic drug, and relieves bronchospasms.
Dexetimide
go.drugbank.com/drugs/DB08997ApprovedWithdrawnA muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.
Categories: Heterocyclic Compounds, 1-RingDemexiptiline
go.drugbank.com/drugs/DB08998ExperimentalIt is a tricyclic antidepressant which acts primarily as a norepinephrine reuptake inhibitor.
Cyclopentamine
go.drugbank.com/drugs/DB08999ApprovedWithdrawnCyclopentamine is a sympathomimetic alkylamine, classified as a vasoconstrictor. Cyclopentamine was an over the counter treatment for nasal congestion in Europe and Australia. … It has been widely discontinued due to the safety, effectiveness, and availability of a similar drug, propylhexedrine.
Chlorphenoxamine
go.drugbank.com/drugs/DB09007ApprovedWithdrawnChlorphenoxamine is marketed under the name Phenoxene. It is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.
Mixtures: SISTRAL C DRAJE , 20 ADETSynonyms: ETHENAMINE, 2-(1-(4-CHLOROPHENYL)-1-PHENYLETHOXY)-N,N-DIMETHYL-, 2-((P-CHLORO-.ALPHA.-METHYL-.ALPHA.-PHENYLBENZYL)OXY)-N,N-DIMETHYLETHYLAMINECarmofur
go.drugbank.com/drugs/DB09010ApprovedWithdrawnCarmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
Categories: Heterocyclic Compounds, 1-RingBromopride
go.drugbank.com/drugs/DB09018InvestigationalBromopride is a dopamine antagonist used as an antiemetic. Its prokinetic properties are similar to those of metoclopramide. It is unavailable in America or the United Kingdom.
Mixtures: ENZYMED®TABLETAS RECUBIERTASSynonyms: 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamideBenzoctamine
go.drugbank.com/drugs/DB09021ExperimentalBenzoctamine is a drug with two main uses. It can be used as a sedative which does not depress the respiratory system, but rather stimulates it. … It can also be used as an anxiolytic with the same efficacy as chlordiazepoxide for treating anxiety neurosis.
Synonyms: N-Methyl-9,10-ethanoanthracene-9(10H)-methanamineCytisine
go.drugbank.com/drugs/DB09028InvestigationalCytisine is a partial nicotinic acetylcholine agonist with a half-life of 4.8 hours. … Recent Phase III clinical trials using Tabex (a brand of Cytisine marketed by Sopharma AD) have shown similar efficacy to varenicline, but at a fraction of the cost.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido[1,2a][1,5]diazocin-8-one