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Flezurafenib
go.drugbank.com/drugs/DB21725ExperimentalFlezurafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Flezurafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor. … Flezurafenib has a monoisotopic molecular weight of 456.16 Da.
Thienylfentanyl
go.drugbank.com/drugs/DB09180ExperimentalIllicitThienylfentanyl has a similar synthesis pathway to fentanyl except 2-(2-bromoethyl)thiophene is substituted for phenethyl bromide. … Thienylfentanyl is a fentanyl analog analgesic that was sold on the black market in the 1980s until the Federal Analog Act scheduled drugs based on structural similarity rather than scheduling drugs individually
CHO Cells Recombinant Vaccine
go.drugbank.com/drugs/DB15893ExperimentalThe vaccine candidate is sponsored by Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. and is undergoing phase I clinical trials to evaluate safety and tolerability. … This vaccine candidate, developed in China, uses SARS-CoV-2 protein subunits that are entirely engineered, created, and secreted by Chinese Hamster Ovary (CHO) cells[A219758].
Budigalimab
go.drugbank.com/drugs/DB16668InvestigationalBudigalimab is under investigation in clinical trial NCT04807972 (Study to Evaluate Adverse Events and Change in Disease Activity When Intravenous (IV) Infusion of ABBV-927 Is Administered in Combination
Androstenediol
go.drugbank.com/drugs/DB01524ExperimentalIllicitto a 3-keto group (3-hydroxysteroid dehydrogenases). … Androstenediol, derived from dehydroepiandrosterone by the reduction of the 17-keto group (17-hydroxysteroid dehydrogenases), is converted to testosterone by the oxidation of the 3-beta hydroxyl group
Synonyms: 5-andendiol, 5-androstenediolMonlunabant
go.drugbank.com/drugs/DB21537InvestigationalMonlunabant is a small molecule drug. The usage of the INN stem '-nabant' in the name indicates that Monlunabant is a cannabinoid receptor antagonist. … Monlunabant is under investigation in clinical trial NCT06542536 (A Research Study Investigating Safety and Concentration in the Blood After One Dose Tablet of the New Medicine Monlunabant in Healthy Weight
Tizaterkib
go.drugbank.com/drugs/DB21296InvestigationalTizaterkib is a small molecule drug. The usage of the INN stem '-terkib' in the name indicates that Tizaterkib is a extracellular signal-regulated kinase (ERK) inhibitor. … Tizaterkib has a monoisotopic molecular weight of 494.2 Da.
Categories: Heterocyclic Compounds, 1-RingMizacorat
go.drugbank.com/drugs/DB21458InvestigationalMizacorat is a small molecule drug. The usage of the INN stem '-corat' in the name indicates that Mizacorat is a glucocorticoid receptor agonist. … Mizacorat is under investigation in clinical trial NCT04556760 (Study to Assess the Effect on Glucose Homeostasis of Two Dose Levels of AZD9567, Compared to Prednisolone, in Adults With Type 2 Diabetes
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingVerpasep caltespen
go.drugbank.com/drugs/DB04959InvestigationalE7 protein is involved in carcinogenesis of anal and cervical tumors, and represents a tumor antigen that may be specifically targeted by lymphocytes. … Verpasep caltespen is a recombinant chimeric protein composed of the heat shock protein 65 (Hsp65) from _Mycobacterium bovis_, and the human papilloma viral (HPV) protein E7.
Tanaproget
go.drugbank.com/drugs/DB04787ExperimentalIt is a high affinity, high efficacy agonist of the progesterone receptor (PR) with a much more selective binding profile relative to most conventional progestins. … It is currently in the process of being developed for clinical use as a contraceptive by Ligand Pharmaceuticals.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring